膜诱导技术与骨搬运技术治疗慢性骨髓炎的疗效对比分析  

Comparative Analysis of Efficacy of Masquelet Technique and Ilizarov Technique in the Treatment of Chronic Osteomyelitis

作　　者：何冬 郎志刚[1] 林达强 喻杉[1] 郭强 梁玉祥[1] 张旭 李可烨 HE Dong;LANG Zhigang;LIN Daqiang(Sichuan Province Orthopedic Hospital,Sichuan Chengdu 610000,China)

机构地区：[1]四川省骨科医院骨病科,四川成都610000

出　　处：《河北医学》2024年第2期296-301,共6页Hebei Medicine

基　　金：四川省中医药管理局课题,(编号:2018LC027);成都中医药大学课题,(编号:YYZX2019017)。

摘　　要：目的:分析膜诱导(Masquelet)技术与骨搬运(Ilizarov)技术治疗慢性骨髓炎(Chronic osteomyelitis,CO)的临床疗效。方法:将85例CO患者采用随机数字表完全随机分为M组(n=42,Masquelet技术)与I组(n=43,Ilizarov技术)。比较两组治疗效果、康复时间、关节功能、生活质量、术后并发症发生情况。结果:I组治疗效果为优良率略高于M组,但差异无统计学意义(P>0.05)。I组骨愈合及完全负重时间较M组长(P<0.05)。术前两组患者lowa膝关节评分、lowa踝关节评分、WHOQOL-BREF评分比较差异无统计学意义(P>0.05);术后两组患者lowa膝关节评分、lowa踝关节评分、WHOQOL-BREF评分均显著高于术前(P<0.05);手术前后两组lowa膝关节评分、lowa踝关节评分、WHOQOL-BREF评分差值比较差异无统计学意义(P>0.05)。I组针道感染率高于M组(P<0.05)。结论:Masquelet技术与Ilizarov技术治疗CO疗效相当,但Masquelet技术对软组织要求较高,且患者需自体供骨量充足,临床中应视具体情况选择。Objective:To compare the clinical efficacy of Masquelet technique and Ilizarov technique in the treatment of chronic osteomyelitis(CO).Methods:A total of 85 CO patients were randomly divided into two groups by random number table:M group(n=42,Masquelet technique)and I group(n=43,Ilizarov technique).The treatment effects,rehabilitation time,joint function,quality of life,and postoperative complications were compared between the two groups.Results:The excellent and good rate of treatment effect in group I was slightly higher than that in group M(P>0.05).Bone healing time and complete weight-bearing time in group I were longer compared to group M(P<0.05).There were no statistically significant differences in lowa knee score,lowa ankle score and WHOQOL-BREF scores between two groups before surgery(P>0.05),and the above scores in both groups were significantly higher after surgery than those before surgery(P<0.05).There was no significant difference in the changes in the lowa knee score,lowa ankle score,and WHOQOL-BREF score between the two groups before and after surgery(P>0.05).The needle tract infection rate in the I group was higher than that in the M group(P<0.05).Conclusion:Masquelet technology and Ilizarov technology are similar to the efficacy of CO treatment,but Masquelet technology has higher requirements for soft tissues,and patients need to have sufficient self-donor bone mass,which should be selected clinically according to the specific circumstances.

关 键 词：慢性骨髓炎 膜诱导技术 骨搬运技术 

分 类 号：R551.3[医药卫生—血液循环系统疾病]