参梅含片成型工艺研究  

Study on Forming Process of Shenmei Buccal Tablets(参梅含片)

作　　者：翁燕[1] 管敏[1] 戴国友[1] WENG Yan;GUAN Min;DAI Guoyou(Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing Jinagsu 210029,China)

机构地区：[1]南京中医药大学附属医院,江苏南京210029

出　　处：《中医药导报》2024年第1期46-50,共5页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：江苏省中医院院级创新发展基金专项课题(Y2020CX78)。

摘　　要：目的:优选参梅含片的成型工艺。方法:采用单因素试验确定辅料种类。采用Design-Expert响应面法,以口感、崩解时限为评价指标,确定主要辅料的用量。结果:得到参梅含片的最优处方为参梅浸膏100 g,乳糖300 g,微晶纤维素100 g,甜菊糖苷4 g。结论:试验所得参梅含片的制备工艺合理、可行。Objective:To optimize the forming process of Shenmei buccal tablets.Methods:Single factor experiment was applied to determine the adjuvant material of prescription.The amount of each adjuvant material was studied by the Design-Expert response surface method with taste and disintegration time as indices.Results:The optimum prescription of Shenmei buccal tablets were Shenmei extract 100 g,lactose 300 g,MCC 100 g,and stevioside 4 g.Conclusion:The preparation technology is reasonable and feasible for the industrial production of Shenmei buccal tablets.

关 键 词：参梅含片 Design-Expert响应面法 口感 崩解时限 

分 类 号：R283.6[医药卫生—中药学]