3.0T磁共振动态增强扫描联合弥散加权成像对宫颈癌病理分期的诊断价值  

Diagnostic value of 3.0T dynamic contrast enhanced magnetic resonance imaging combined with diffusion weighted imaging for pathological staging of cervical cancer

作　　者：黄俊[1] 吴彬彬[1] 徐泉鸿 HUANG Jun;WU Binbin;XU Quanhong(Medical Imaging Center,Navy Anqing Hospital,Anqing 246003,Anhui,China)

机构地区：[1]海军安庆医院影像中心,安徽省安庆市246003

出　　处：《广西医学》2023年第22期2691-2695,共5页Guangxi Medical Journal

基　　金：安庆市医疗卫生类自筹经费科技计划项目(2022Z4003)。

摘　　要：目的 探讨3.0T磁共振动态增强扫描(DCE-MRI)联合弥散加权成像(DWI)对宫颈癌病理分期的诊断价值。方法 选择70例宫颈癌患者作为研究组,50例同期进行妇科常规检查并排除宫颈癌变者作为对照组,两组均进行常规MRI平扫、DWI扫描与DCE-MRI扫描,获取表观弥散系数(ADC)、容量转移常数(Ktrans)、速率常数(Kep)、血管外细胞外容积分数(Ve)。比较研究组与对照组之间,以及不同病理分期宫颈癌患者之间的Kep、Ktrans、Ve及ADC。以术后病理活检结果为金标准,分析3.0T DCE-MRI联合DWI在宫颈癌病理分期中的诊断价值。结果 研究组ADC低于对照组,Kep、Ktrans、Ve高于对照组(P<0.05)。随着宫颈癌病理分期严重程度的增加,ADC逐渐降低,Kep、Ktrans、Ve逐渐升高(P<0.05)。3.0T DCE-MRI联合DWI诊断宫颈癌病理分期结果与宫颈癌术后病理活检结果的一致性较高(Kappa值=0.871,P=0.043,95%CI:0.787,0.955)。结论 3.0T DCE-MRI联合DWI在宫颈癌病理分期中的诊断价值较高,临床可根据其诊断结果及时采取治疗措施,控制患者病情,从而改善患者预后。Objective To explore the diagnostic value of 3.0T dynamic contrast enhanced magnetic resonance imaging(DCE-MRI) combined with diffusion weighted imaging(DWI) for pathological staging of cervical cancer.Methods A total of 70 patients with cervical cancer were selected as study group,and another 50 individuals who conducted gynecological routine examination and were excluded from cervical carcinogenesis during the same period were selected as control group.Both groups received routine MRI plain scan,DWI scan,and DCE-MRI scan for obtaining apparent diffusion coefficient(ADC),capacity transfer constant(Ktrans),rate constant(Kep),and extravascular extracellular volume fraction(Ve).Kep,Ktrans,Ve,and ADC were compared between the study group and the control group,and between patients with cervical cancer in different pathological staging.With postoperative pathological biopsy result as the gold standard,the diagnostic value of 3.0T DCE-MRI combined with DWI for pathological staging of cervical cancer was analyzed.Results The study group exhibited lower ADC,whereas higher Kep,Ktrans,and Ve as compared with the control group(P<0.05).With the severity increase of pathological staging of cervical cancer,ADC was gradually decreased,while Kep,Ktrans,and Ve were gradually elevated(P<0.05).3.0T DCE-MRI combined with DWI for the diagnosis of cervical cancer pathological staging results was relatively highly consistent with the results of postoperative pathological biopsy of cervical cancer(Kappa value=0.871,P=0.043,95% CI:0.787,0.955).Conclusion 3.0T DCE-MRI combined with DWI exerts a relatively high diagnostic value for pathological staging of cervical cancer.According to the diagnostic results,timely treatment measures can be taken to control patients′ disease condition,so as to ameliorate patients′ prognosis.

关 键 词：宫颈癌 3.0T磁共振动态增强扫描 弥散加权成像 病理分期 

分 类 号：R445.2[医药卫生—影像医学与核医学]