HFR对血液透析患者瘙痒症状缓解的案例分析研究  

Case study on the hemodiafiltration with endogenous reinfusion to relieve pruritus symptoms in hemodialysis patients

作　　者：刘鹏程 宋锴[2] 曾颖[1] 马琴 胡东艳 谭丽萍[3] 姜小梅[1] LIU Peng-cheng;SONG Kai;ZENG Ying;MA Qin;HU Dong-yan;TAN Li-ping;JIANGXiao-mei(Blood Purification Center of Department of Nephrology,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China;Department of Nephrology,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China;Department of Nursing,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China)

机构地区：[1]苏州大学附属第二医院肾内科血液净化中心,苏州215004 [2]苏州大学附属第二医院肾内科,苏州215004 [3]苏州大学附属第二医院护理部,苏州215004

出　　处：《中国血液净化》2024年第1期18-21,共4页Chinese Journal of Blood Purification

摘　　要：目的观察一种新型血液透析技术—内源性再输注血液透析滤过(hemodiafiltration with endogenous reinfusion,HFR)对缓解血液透析患者瘙痒症状的效果。方法行前后对照研究,比较患者HFR治疗前、后瘙痒症状、睡眠质量、生活质量和相关实验室检查指标。结果HFR治疗前、后瘙痒严重程度(Z=-2.023,P=0.043)、睡眠质量(t=7.318,P<0.001)和生活质量(t=4.804,P=0.003)差异均有统计学意义。结论HFR治疗在一定程度上可减轻尿毒症患者的瘙痒症状,改善其睡眠质量和生活质量。Objectives To observe the effect of the new hemodialysis technology-hemodiafiltration with endogenous reinfusion(HFR)in the treatment of pruritus in patients undergoing hemodialysis.Methods Clinical controlled studies including pruritus symptoms,quality of sleep,quality of life and laboratory tests were performed before and after HFR.Results There were significant differences in severity of itching(Z=-2.023,P=0.043),quality of sleep(t=7.318,P<0.001)and quality of life(t=4.804,P=0.003)before and after HFR treatment(P<0.05).Conclusion HFR can reduce the pruritus symptoms in a short period of time,and improve the quality of sleep and quality of life in uremic patients.

关 键 词：内源性再输注血液透析滤过 血液透析 尿毒症 皮肤瘙痒 

分 类 号：R459.5[医药卫生—治疗学]