静脉-动脉血二氧化碳分压差的临床意义及应用研究进展  

Clinical significance and application research progress of venous-arterial carbon dioxide partial pressure difference

作　　者：罗荣 莫桂熙 LUO Rong;MO Guixi(Department of Anesthesiology,The First Clinical Medical College of Guangdong Medical University(Meizhou People'sHospital),Zhanjiang,Guangdong 524023,China;Department of Anesthesiology,Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong 524023,China)

机构地区：[1]广东医科大学第一临床医学院<梅州市人民医院>麻醉科,广东湛江524023 [2]广东医科大学附属医院麻醉科,广东湛江524023

出　　处：《医药前沿》2024年第3期40-43,共4页Journal of Frontiers of Medicine

摘　　要：血流动力学失稳是危重患者救治中普遍存在的问题,其实质是机体低灌注和氧气代谢异常。如果在早期未得到有效的治疗,就会出现多个脏器的功能障碍,甚至会对患者的预后产生重要的影响。在肿瘤早期诊断和治疗中,对局部血流进行检测和校正非常有必要。中心静脉血氧饱和度(ScvO_(2))、乳酸、中心静脉压(CVP)等常规检测方法对机体的代谢影响不大,而中心静脉-动脉血二氧化碳分压差(Pcv-aCO_(2))能更灵敏地反映机体血流灌注及血流动力学,对临床治疗及预防感染所致的慢性疾病具有重要的临床价值。本文对Pcv-aCO_(2)在脓毒性休克、失血性休克、重度烧伤、颅脑损伤、外科手术和心血管疾病中的临床意义进行综述。Hemodynamic instability is a common problem in the treatment of critically ill patients,and its essence is hypoperfusion and abnormal oxygen metabolism.If it is not treated effectively in the early stage,there will be dysfunction of multiple organs,which will even have an important impact on the prognosis of patients.In the early diagnosis and treatment of tumor,it is very necessary to detect and correct the local blood flow.Conventional detection methods such as central venous oxygen saturation(ScvO_(2)),lactic acid and central venous pressure(CVP)have little influence on the metabolism of the body,while the central venous-arterial partial pressure of carbon dioxide(Pcv-aCO_(2))can reflect the blood perfusion and hemodynamics of the body more sensitively,which has important clinical value for clinical treatment and prevention of chronic diseases caused by infection.This article summarizes the role of Pcv-aCO_(2) in septic shock,hemorrhagic shock,severe burn,craniocerebral injury,surgery and cardiovascular diseases.

关 键 词：综述 中心静脉-动脉血二氧化碳分压差 中心静脉血氧饱和度 临床意义 应用 

分 类 号：R543.5[医药卫生—心血管疾病]