调经助孕合剂联合调经促孕十三针治疗卵泡发育不良型不孕症的效果  

Effect analysis of combined Tiaojingzhuyun mixture and regulating menstration and promoting pregnancy by thirteen acupuncture in treating infertility caused by Follicle dysplasia

作　　者：陈茜 汪新妮 亓媛 胡书香 李津 CHEN Xi;WANG Xinni;QI Yuan;HU Shuxiang;LI Jin(Department of Gynecology,Wuhan Hospital of Traditional Chinese Medicine,Wuhan 430014,China;不详)

机构地区：[1]武汉市中医医院妇科,武汉430014 [2]武汉科技大学公共卫生学院,武汉430081

出　　处：《实用医学杂志》2024年第3期412-416,共5页The Journal of Practical Medicine

基　　金：湖北省卫健委中医药科研资助项目(编号:MY2021M019);武汉市卫生健康委科研资助项目:(编号:WZ20A05);武汉市科技局科研资助项目(编号:2022020801010583)。

摘　　要：目的探讨调经助孕合剂联合调经促孕十三针治疗卵巢功能下降(DOR)合并卵泡发育不良型不孕症的临床效果。方法将DOR卵泡发育不良不孕症患者60例随机分为观察组(调经助孕合剂+调经促孕十三针+氯米芬组)和对照组(氯米芬组),各30例。观察患者治疗后卵泡刺激素、最大卵泡大小及排卵情况、子宫动脉血流指标、内膜厚度及妊娠等改善情况。结果观察组治疗后的卵泡刺激素、最大卵泡大小、内膜厚度及子宫动脉血流指标改善情况均优于对照组,差异有统计学意义(P<0.05)。观察组排卵率66.7%,妊娠率40%;高于对照组排卵率40%,妊娠率20%,差异有统计学意义(P<0.05)。结论调剂助孕合剂联合调经促孕十三针用于DOR卵泡发育不良不孕症的患者,可改善卵泡刺激素水平,促进卵泡成熟及排卵,增厚子宫内膜,降低子宫动脉血流阻力,提高妊娠率,且不良反应少,临床疗效较好。Objective To explore the clinical effects of Tiaojing Zhuyun mixture combined with regulating menstration and promoting pregnancy by thirteen acupuncture in the treatment of Declining Ovarian Function(DOR)combined with follicular dysplasia infertility.Methods From January 1,2022 to January 1,2023,60 cases of infertility patients with DOR follicular dysplasia were treated in our hospital,and the above cases were randomly divided into experimental group:Tiaojing Zhuyun mixture+regulating menstration and promoting pregnancy by thirteen acupuncture+Clomiphene group;Control group:Clomiphene group,30 cases each.The improvement of FSH,maximum follicle size and ovulation,uterine artery blood flow index,endometrial thickness and pregnancy were observed after treatment.Results The improvement of follicle stimulating hormone,maximum follicle size,endometrial thickness and uterine artery blood flow indexes in Tiaojing Zhuyun mixture+regulating menstration and promoting pregnancy by thirteen acupuncture+Clomiphene group were better than clomiphene group.The difference between groups was statistically significant(P<0.05).The ovulation rate was 66.7%and the pregnancy rate was 40%.The ovulation rate was 40%higher than the control group,and the pregnancy rate was 20%.The difference between groups was statistically significant(P<0.05).Conclusion In the patients with DOR follicular dysplasia infertility,Tiaojing Zhuyun mixture combined with regulating menstration and promoting pregnancy by thirteen acupuncture can improve the level of follicle stimulating hormone,promote follicular maturation and ovula⁃tion,reduce the resistance of uterine artery blood flow,increase the thickness of endometrial,promote pregnancy,and have fewer adverse reactions.

关 键 词：调经助孕合剂 调经促孕十三针 卵巢功能下降 卵泡发育不良 不孕症 

分 类 号：R271.14[医药卫生—中医妇科学]