环泊酚与瑞马唑仑复合阿芬太尼用于宫腔镜手术的麻醉效果  

Anesthetic efficacy of ciprofol combined with alfentanil and remazolam besylate combined with alfentanil in hysteroscopy

作　　者：朱娟[1] 马鹏 蒋鹏[1] ZHU Juan;MA Peng;JIANG Peng(Department of Anesthesiology,Affiliated Hospital,Jiangsu University,Zhenjiang 212000,CHINA)

机构地区：[1]江苏大学附属医院麻醉科,江苏镇江2120000

出　　处：《江苏医药》2024年第1期67-70,共4页Jiangsu Medical Journal

基　　金：镇江市社会发展指导性科技计划项目(FZ2020032)。

摘　　要：目的 比较环泊酚与瑞马唑仑复合阿芬太尼用于宫腔镜手术的麻醉效果。方法 64例行宫腔镜手术患者随机分为两组,每组32例。麻醉诱导分别静脉缓慢推注环泊酚0.4 mg/kg+阿芬太尼10μg/kg(A组)和瑞马唑仑0.2 mg/kg+阿芬太尼10μg/kg(B组)。记录麻醉诱导前(T1)、麻醉诱导后SBP最低时(T2)和麻醉苏醒后(T3)的HR、SBP、DBP和SpO_(2)。比较两组麻醉相关指标。评估患者术后认知功能和VAS疼痛评分。记录不良反应发生情况。结果 A组麻醉诱导时间和苏醒时间均少于B组(P<0.05),两组手术时间相仿(P>0.05)。两组T1~T3时HR、BP和SpO_(2)相仿(P>0.05)。A组注射痛发生率低于B组(P<0.05)。两组术后简易智力状态检查量表评分和VAS疼痛评分差异均无统计学意义(P>0.05)。结论 环泊酚与瑞马唑仑复合阿芬太尼用于宫腔镜手术麻醉有效、安全。与瑞马唑仑复合阿芬太尼相比,环泊酚复合阿芬太尼麻醉诱导时间和苏醒时间短,注射痛发生率低。Objective To compare the anesthetic efficacy of ciprofol combined with alfentanil and remazolam besylate combined with alfentanil in hysteroscopy.Methods Sixty-four patients undergoing hysteroscopic surgery were randomized into two groups with 32 cases each.Anesthesia induction was performed by slowly intravenous injection of ciprofol 0.4 mg/kg plus alfentanil 10 μg/kg in group A or remazolam besylate 0.2 mg/kg plus alfentanil 10 μg/kg in group B.The HR,SBP,DBP and SpO_(2) were recorded before anesthesia induction(T1),at the lowest SBP after anesthesia induction(T2) and after anesthesia recovery(T3).The anesthesia-related indicators were compared between the two groups.The postoperative cognitive function and VAS pain score were evaluated.The occurrence of adverse reaction was recorded.Results The anesthesia induction time and recovery time of group A were significantly shorter than those of group B(P<0.05).The operation times of the two groups were similar(P>0.05).There were no significant differences in HR,BP,SpO_(2) at T1 to T3 between the two groups(P>0.05).The incidence of injection pain in group A was significantly lower than that in group B(P<0.05).There was no significant difference in the mini-mental state examination score and VAS pain score between the two groups(P>0.05).Conclusion Both anesthesia induction with ciprofol combined with alfentanil and remazolam besylate combined with alfentanil for hysteroscopic surgery are effective and safe.Anesthesia induction with ciprofol combined with alfentanil has relatively shorter anesthesia induction time and recovery time, and lower incidence of injection pain.

关 键 词：环泊酚 瑞马唑仑 阿芬太尼 宫腔镜 

分 类 号：R614[医药卫生—麻醉学]