红细胞输注指征的研究现状与进展  

The present situation and advance of red blood cell transfusion triggers

作　　者：陈宇业 吕红 李倩 申婧佳 石佳 CHEN Yuye;LYU Hong;LI Qian;SHEN Jingjia;SHI Jia(Department of Anesthesiology,Fuwai Hosipital,Chinese Academy of Medical Science&Peking Union Medical College,Beijing 100037,China.)

机构地区：[1]中国医学科学院阜外医院麻醉中心,北京100037

出　　处：《中国输血杂志》2024年第2期238-243,共6页Chinese Journal of Blood Transfusion

摘　　要：在临床实践中,红细胞输注需要参考患者的血红蛋白浓度水平,但不同指南推荐的红细胞输注启动阈值都不尽相同。这些不同范围的存在导致输血启动的时机也仍有争议。同时,使用异体血制品就存在着一定发生输血相关感染性损伤或器官损伤的风险,因此启动红细胞输注需要更多循证医学证据。本文综述了中心静脉氧饱和度、动静脉氧差和近红外光谱法这3种新指标以及围术期输血指征评分等新方法来帮助评估输血指征,为临床医生进行输血决策提供参考。In clinical practice,red blood cell infusion needs to be based on the patient′s hemoglobin level.However,different guidelines recommend different thresholds for red blood cell infusion and the timing of blood transfusion initiation is still controversial due to the presence of these different thresholds.Meanwhile,the use of allogeneic blood products carries a certain risk of transfusion-related infections or organ damage.Therefore,initiating red blood cell infusion requires more evidence.This review discusses some new methods,namely central venous oxygen saturation,arterial venous oxygen difference,near-infrared spectroscopy,and perioperative transfusion trigger score.It aims to help evaluate blood transfusion trigger and provide reference for doctors when making transfusion decisions.

关 键 词：输血/成分输血 限制性输血策略 围术期管理 血液保护 

分 类 号：R457.1[医药卫生—治疗学] R331.141[医药卫生—临床医学]