细针抽吸活检与术中快速冰冻切片在甲状腺结节诊断中的应用分析  

Application Analysis of Fine Needle Aspiration Biopsy and Intraoperative Rapid Frozen Sectionin the Diagnosis of Thyroid Nodules

作　　者：王燕 胡惠敏[1] Wang Yan;Hu Huimin(Suzhou Xiangcheng People′s Hospital,Suzhou,Jiangsu 215100,China)

机构地区：[1]苏州市相城人民医院,江苏苏州215100

出　　处：《大理大学学报》2024年第2期63-66,共4页Journal of Dali University

摘　　要：目的:探讨细针抽吸活检(FNAB)细胞学和术中快速冰冻切片组织学检查在甲状腺结节中的诊断应用价值。方法:回顾性分析2021年4月至2023年4月苏州市相城人民医院收治的180例甲状腺结节患者临床病理资料,对比分析FNAB细胞学与术中快速冰冻切片组织学诊断的准确度、敏感度、特异度。结果:FNAB细胞学诊断良性病变52例,恶性病变128例,检查准确度、敏感度、特异度分别为92.2%、91.1%、95.6%;术中快速冰冻切片组织学诊断良性病变55例,恶性病变125例,检查准确度、敏感度、特异度分别为91.1%、88.9%、97.8%。2种诊断方法结果比较,差异无统计学意义(P>0.05)。结论:FNAB细胞学具有操作简便、准确率高和标本获取率高等特点,术中快速冰冻切片具有高时效性、边缘定位清晰等特点,二者相互印证,互为补充,对甲状腺结节性质的诊断具有重要的临床应用价值。Objective:To explore the diagnostic value of fine needle aspiration biopsy(FNAB)cytology and intraoperative rapid frozen section histopathology in thyroid nodules.Methods:A retrospective analysis was conducted on clinical pathological data of 180 patients with thyroid nodules treated at Suzhou Xiangcheng People′s Hospital from April 2021 to April 2023.The accuracy,sensitivity,and specificity of FNAB cytology and intraoperative rapid frozen section histopathology were compared and analyzed.Results:FNAB cytology diagnosed 52 cases of benign lesions and 128 cases of malignant lesions,with an accuracy,sensitivity,and specificity of 92.2%,91.1%,and 95.6%,respectively.Intraoperative rapid frozen section histopathology diagnosed 55 cases of benign lesions and 125 cases of malignant lesions,with an accuracy,sensitivity,and specificity of 91.1%,88.9%,and 97.8%,respectively.There was no statistically significant difference between the two diagnostic methods(P>0.05).Conclusion:FNAB cytology is characterized by simple operation,high accuracy,and a high specimen acquisition rate.Intraoperative rapid frozen section has the advantages of high efficiency and clear margin localization.The two methods mutually confirm and complement each other,providing important clinical value in the diagnosis of the nature of thyroid nodules.

关 键 词：甲状腺结节 细针抽吸活检 快速冰冻切片 组织学检查 

分 类 号：R581[医药卫生—内分泌]