自体纳米脂肪移植治疗慢性难愈性创面的临床研究  

Clinical Research on the Treatment of Chronic Refractory Wounds with Autologous Nanofat Transplantation

作　　者：陈从柏 赵领财 王德运 王浩 朱敏[1] 尹青山[1] CHEN Congbai;ZHAO Lingcai;WANG Deyun;WANG Hao;ZHU Min;YIN Qingshan(Department of Burn and Plastic Surgery,Tianmen First People's Hospital,Tianmen 431700,Hubei,China;Department of Burns,Wuhan Third Hospital,Wuhan 430074,Hubei,China)

机构地区：[1]天门市第一人民医院烧伤整形科,湖北天门431700 [2]武汉市第三医院烧伤科,湖北武汉430074

出　　处：《中国美容医学》2024年第2期24-28,共5页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨自体纳米脂肪移植治疗慢性难愈性创面的临床疗效。方法:选择2018年9月-2020年5月笔者医院收治的47例慢性难愈性创面患者为研究对象,根据治疗方式的不同分为观察组(24例)和对照组(23例)。两组患者均进行彻底清创,观察组创面行自体纳米脂肪移植治疗,对照组不予纳米脂肪移植,两组均采用“邮票”植皮来闭合创面。比较两组创面愈合及并发症发生情况。结果:术后3周,观察组创面愈合率高于对照组、创面疼痛评分低于对照组(P<0.05);观察组并发症发生率低于对照组、创面愈合时间短于对照组(P<0.05)。结论:采用自体纳米脂肪移植治疗慢性难愈性创面,可提高创面愈合率,减轻创面疼痛,减少感染等并发症,具有较好的临床效果。Objective To investigate the clinical efficacy of autologous nanofat transplantation in the treatment of chronic refractory wounds.Methods Forty-seven patients with chronic refractory wounds admitted to the author's hospital from September 2018 to May 2020 were selected as the research objects.According to the different treatment methods,they were divided into observation group(24 cases)and control group(23 cases).The wounds in the observation group were treated with autologous nanofat transplantation,while the wounds in the control group were not treated with nanofat transplantation.Both groups chose"stamp"skin grafting after skin flap to close the wound.The wound healing and complications were compared between the two groups.Results Three weeks after operation,the wound healing rate of the observation group was higher than that of the control group,and the wound pain score was lower than that of the control group(P<0.05).The incidence of complications in the observation group was lower than that in the control group,and the wound healing time was shorter than that in the control group(P<0.05).Conclusion Autologous nanofat transplantation in the treatment of chronic refractory wounds can improve the wound healing rate,reduce wound pain,reduce complications such as infection,and has good clinical effects.

关 键 词：纳米脂肪 脂肪来源干细胞 慢性难愈性创面 脂肪移植 创面愈合 

分 类 号：R622.9[医药卫生—整形外科]