rh-aFGF凝胶联合点阵CO_(2)激光治疗对剖宫产术后切口瘢痕愈合和美观满意度的影响  

Effects of rh-aFGF Gel Combined with Fractional CO_(2) Laser on Incision Scar Healing and Aesthetics Satisfaction after Cesarean Section

作　　者：粟东林 刘洋[2] SU Donglin;LIU Yang(Department of Dermatology,Dazu Hospital Affiliated to Chongqing Medical University,Chongqing 402360,China;Department of Obstetrics and Gynecology,Dazu Hospital Affiliated to Chongqing Medical University,Chongqing 402360,China)

机构地区：[1]重庆医科大学附属大足医院皮肤科,重庆402360 [2]重庆医科大学附属大足医院妇产科,重庆402360

出　　处：《中国美容医学》2024年第2期94-97,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨重组人酸性成纤维细胞生长因子(Recombinant Human acidic fibroblast growth factor,rh-aFGF)凝胶联合点阵CO_(2)激光治疗对剖宫产术后切口瘢痕愈合和美观满意度的影响。方法:选取2020年6月-2022年6月在笔者医院收治的85例剖宫产术后皮肤瘢痕患者,根据治疗方法将其分为对照组(42例)和联合组(43例)。对照组在患者剖宫产术后3个月左右瘢痕出现后采取点阵CO_(2)激光治疗,联合组在对照组基础上予以rh-aFGF凝胶联合治疗。观察比较两组患者治疗前、治疗后1个月、治疗后3个月和治疗后6个月时的温哥华瘢痕量表(Vancouver scar scale,VSS)评分情况,治疗3个月时的临床治愈情况、美观满意度和不良反应发生情况。结果:治疗后1个月、3个月和6个月时,联合组VSS评分均低于对照组,且联合组临床总治愈率和美观满意度均较对照组高(P<0.05);联合组不良反应发生率低于对照组(P<0.05)。结论:相比于单纯使用点阵CO_(2)治疗,rh-aFGF凝胶联合点阵激光治疗对剖宫产术后切口瘢痕愈合效果更好,能有效提高患者对瘢痕恢复的满意程度,且不增加患者不良反应。Objective To explore the effects of recombinant human acidic fibroblast growth factor(rh-aFGF)gel combined with fractional CO_(2) laser on incision scar healing and aesthetics satisfaction after cesarean section.Methods A total of 85 patients with skin scars after cesarean section in the hospital were enrolled between June 2020 and June 2022.According to different treatment methods,they were divided into control group(42 cases)and combination group(43 cases).On basis of routine treatment,control group was treated with fractional CO_(2) laser at about 3 months after surgery,while combination group was treated with rh-aFGF gel on the basis of control group.The scores of Vancouver scar scale(VSS)before treatment,at 1 month,3 months and half a year after treatment,clinical healing,aesthetics satisfaction and occurrence of adverse reactions at 3 months after treatment were observed and compared between the two groups.Results At 1 month,3 months and half a year after treatment,VSS scores in combination group were lower than those in control group.At treatment,total clinical healing rate and aesthetics satisfaction in combination group were higher than those in control group(P<0.05).The incidence of adverse reactions during treatment was lower in the combination group than in the control group(P<0.05).Conclusion Compared with fractional CO_(2) laser alone,rh-aFGF gel combined with fractional CO_(2) laser has better healing effect of incision scars after cesarean section,which can effectively improve patients satisfaction with scar recovery and will not increase adverse reactions.

关 键 词：剖宫产术后切口瘢痕 美观满意度 点阵CO_(2)激光 重组人酸性成纤维细胞生长因子 

分 类 号：R764.9[医药卫生—耳鼻咽喉科]