岷山红三叶草异黄酮对运动大鼠免疫功能及运动能力的影响  

The Effect of Isoflavones of Minshan Red Clover on Immune Function and Exercise Capacity in Exercise Rats

作　　者：赵亮[1] Zhao Liang(Lanzhou University,Lanzhou 730030,China)

机构地区：[1]兰州大学,甘肃兰州730030

出　　处：《体育科技文献通报》2024年第1期265-267,共3页Bulletin of Sport Science & Technology

摘　　要：目的:研究岷山红三叶草异黄酮对大鼠免疫功能及运动能力的影响。方法:将40只大鼠随机均分为四组:安静组、安静给药组、运动组和运动给药组,建立递增运动负荷大鼠模型,测量运动大鼠力竭时间、免疫脏器指数、大鼠免疫球蛋白及T淋巴细胞亚群含量。结果:经过6周的大强度运动,服用岷山红三叶草异黄酮大鼠组与相应的对照组比较,其力竭运动时间明显延长,免疫脏器指数和T淋巴细胞亚群(CD_(4)^(++)、CD_(8)^(+)、CD_(4)^(+)/CD_(8)^(+))、免疫球蛋白(IgA、IgG、IgM)的含量均有明显上升和变化。结论:(1)岷山红三叶草异黄酮可明显提高大强度耐力训练大鼠力竭运动时间,提高运动能力;(2)岷山红三叶草异黄酮对运动大鼠的免疫系统产生影响,可以通过调节免疫细胞的功能,增强机体的免疫能力,并且对免疫抑制有一定改善。OBJECTIVE:This study aims to investigate the influence of isorhamnetin derived from Minshan red clover on immune function and exercise capacity in rats.METHODS:Forty rats were randomly divided into four groups:sedentary group,sedentary with isorhamnetin group,exercise group,and exercise with isorhamnetin group.An incremental exercise load rat model was established to measure exhaustion time,immune organ index,immune globulins,and T lymphocyte subpopulations.RESULTS:After 6 weeks of high-intensity exercise,rats treated with isorhamnetin from Minshan red clover exhibited a significant extension in exhaustion time compared to the corresponding control group.Moreover,there were noticeable increases and variations in immune organ index,T lymphocyte subpopulations(CD_(4)^(++),CD_(8)^(+),CD_(4)^(+)/CD_(8)^(+))、and immune globulin levels(IgA,IgG,IgM).CONCLUSIONS:(1)Isorhamnetin from Minshan red clover can markedly enhance exhaustion time in rats undergoing high-intensity endurance training,thereby improving exercise capacity.(2)Isorhamnetin from Minshan red clover impacts the immune system in exercised rats by modulating immune cell function,enhancing immune capabilities,and demonstrating some amelioration in immune suppression.

关 键 词：岷山红三叶 异黄酮 免疫机能 运动能力 

分 类 号：G804[文化科学—运动人体科学]