重构本草——金樱子  

Reconstruction of Chinese materia medica-cherokee rose fruit

作　　者：杨校 刘治彤 王丽[2] 柯于鹤[3] YANG Xiao;LIU Zhitong;WANG Li;KE Yuhe(Wuhan Hankou Hospital,Wuhan 430012,China;Hubei University of Chinese Medicine,Wuhan 430065,China;Wuhan Hospital of Integrated Traditional Chinese and Western Medicine,Wuhan 430022,China)

机构地区：[1]武汉市汉口医院,武汉430012 [2]湖北中医药大学,武汉430065 [3]武汉市中西医结合医院,武汉430022

出　　处：《长春中医药大学学报》2024年第2期140-143,共4页Journal of Changchun University of Chinese Medicine

基　　金：中国科学院学部咨询评议项目(2021-ZW10-A-017)。

摘　　要：通过古籍文献调研、中医药现代研究成果的梳理,结合中医临床及中药学等学科领域内知名专家学者的认识及应用经验,归纳出金樱子:功效主要为固精缩尿,固崩止带,涩肠止泻。症靶为遗精滑精、遗尿尿频、腹泻。标靶为蛋白尿。现代药理发现,金樱子及其有效成分具有改善肾功能、抑菌、抗炎、抗氧化、保肝等作用。本品无毒,但是有实火、邪实者慎服。临床常用剂量为6~45 g,内服时当根据不同疾病,或同一疾病的不同阶段进行辨证使用,并积极探索金樱子用量与症靶、标靶的量效关系构建。Through the investigation of ancient books and the sorting of the modern research achievements of traditional Chinese medicine,combined with the understanding and application experience of well-known experts and scholars in desciplinary felds such as traditional Chinese medicine clinical medicine and science of Chinese materia medica,it is concluded that cherokee rose fruit mainly has the effects of controlling nocturnal emission and reducing urination,arresting leucorrhea and metrorrhagia,and relieving diarrhea with astringents.The symptom targets are nocturnal emission and night emission,enuresis and frequent micturition,and diarrhea.The biochemical indicator target is proteinuria.Modern pharmacological studies have found that cherokee rose fruit and its active ingredients have the effects of improving kidney function,inhibiting bacteria,anti-inflammatory,antioxidant,and protecting the liver.This product is non-toxic,but patients with internal heat or excessive pathogen should use it with caution.The commonly used dosage in clinical practice is 6-45g.When taken orally,it should be used dialectically according to different diseases or different stages of the same disease,and the construction of dose-effect relationship between the dosage of cherokee rose fruit and the symptom target and biochemical indicator target should be explored actively.

关 键 词：金樱子 症靶 标靶 遗精滑精 遗尿尿频 腹泻 蛋白尿 临床回归 

分 类 号：R281[医药卫生—中药学]