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作 者:庞晓燕 王鑫 王晓华 赵建平 PANG Xiaoyan;WANG Xin;WANG Xiaohua;ZHAO Jianping(Inner Mongolian Maternity and Child Health Care Hospital,Hohhot,Inner Mongolia 010020,China;Clinical Medical College,Inner Mongolia Medical University,Hohhot,Inner Mongolia 010010,China;不详)
机构地区:[1]内蒙古自治区妇幼保健院,内蒙古呼和浩特010020 [2]内蒙古医科大学内蒙古临床医学院,内蒙古呼和浩特010010 [3]内蒙古自治区人民医院检验科,内蒙古呼和浩特010017
出 处:《中国病毒病杂志》2023年第6期454-460,共7页Chinese Journal of Viral Diseases
摘 要:人巨细胞病毒(human cytomegalovirus,HCMV)是世界广泛传播的传染病病原体,孕妇妊娠期间感染此病毒后会垂直传染给胎儿,导致胎儿发育异常和智力下降,并可引起新生儿神经发育和听力异常等疾病。新生儿感染后可无症状,因此容易被忽视而产生严重后遗症,影响新生儿的发育和健康。目前国际国内诊治意见尚不统一,对于母婴感染的诊断和新生儿的筛查方面仍存在很多问题。本文结合近年来的专家共识和研究进展,从人巨细胞病毒的病原学特点、流行病学、传播途径、实验室检查、诊断方法和治疗等方面进行综述,以期了解母婴巨细胞病毒感染的临床特点和诊治进展,为临床提供帮助。Human cytomegalovirus(HCMV)is a worldwide infectious disease pathogen,which can be vertically transmitted to the fetuses after mother's infection during pregnancy,resulting in abnormal fetal development and mental decline,and neurological development and hearing abnormalities in the newborns.Neonatal infections can be asymptomatic,so they are easy to be ignored and have serious sequelae,affecting the development and health of the newborns.At present,the international and domestic diagnosis and treatment opinions are not unified,and there are still many problems in the diagnosis of mother-to-child infection and newborn screening.Based on the expert consensus and research progress in recent years,this paper reviews the etiological characteristics,epidemiology,transmission routes,laboratory tests,diagnostic methods and treatment of HCMV in order to understand the clinical characteristics,diagnosis and treatment progress of maternal and infant cytomegalovirus infections,and provide clinical assistance.
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