无锡地区2 529例泌尿系结石成分分析  

Composition analysis of 2529 cases of urinary calculi in Wuxi area

作　　者：张艳 周德琪 华剑红 卫冰冰 Zhang Yan;Zhou Deqi;Hua Jianhong;Wei Bingbing(Department of Urology,the Affiliated Wuxi People′s Hospital of Nanjing Medical University,Wuxi 214023,China)

机构地区：[1]南京医科大学附属无锡人民医院泌尿外科,无锡214023

出　　处：《国际泌尿系统杂志》2024年第1期101-105,共5页International Journal of Urology and Nephrology

摘　　要：目的分析无锡地区2 529例泌尿系结石标本的结石成分, 为泌尿系结石的临床预防和治疗提供参考。方法回顾性分析2009年3月至2021年10月在江苏无锡地区收集的2 529例泌尿系结石标本, 采用红外光谱分析法分析结石成分, 并结合患者的临床资料进行分析。结果共检测出19种结石成分, 其中单一成分结石9种, 共990例;混合成分结石10种, 共1 539例。单一成分结石以草酸钙为主, 共840例;混合成分结石以草酸钙+碳酸磷灰石为主, 共1 335例。草酸钙类和尿酸类结石中男性患者的发生率高于女性患者;而在感染性结石中, 女性患者的发生率高于男性患者(均P<0.05)。36~60年龄段的结石发病人数最多。在各个年龄段中, 发生率最高的结石成分为草酸钙类。尿酸类结石在61~86年龄段的发病率较其他年龄段高, 差异均有统计学意义(均P<0.05)。在各个不同部位, 发生率最高的结石成分为草酸钙类。尿酸类结石在膀胱中的发生率明显高于其他部位, 差异均有统计学意义(均P<0.05)。在各个不同年龄段中, 上尿路结石的发生率明显高于下尿路结石。膀胱结石在61~86年龄段的发生率最高, 与其他年龄段比较, 差异均有统计学意义(均P<0.05)。结论无锡地区泌尿系结石成分主要以草酸钙类结石为主, 草酸钙类结石在不同性别、年龄和部位分布存在差异, 对于泌尿系结石的临床预防和治疗有重要的参考价值。Objective To analyze the composition of 2529 cases of urinary calculi in Wuxi area,and to provide reference for the clinical prevention and treatment of urinary calculi.Methods From March 2009 to October 2021,2529 cases of urinary calculi in Wuxi City,Jiangsu Province were collected.Composition of the urinary calculi were analyzed by urinary calculi infrared light automatic analyzer,and the clinical data of the patients were analyzed.Results A total of 19 kinds of stone components were detected,including 9 kinds of single stone components,a total of 990 cases.There were 1539 cases of 10 kinds of mixed component stones.Calcium oxalate was the main component of the single stone,840 cases.Calcium oxalate+carbonate apatite was the main mixed component of stones,a total of 1335 cases.The incidence of calcium oxalate and uric acid stones in male patients was higher than that in female patients.The incidence of infective stones in female patients was higher than that in male patients(all P<0.05).The number of stones in the age group of 36-60 was the highest.In all age groups,the highest incidence of stone components are calcium oxalates.The incidence of uric acid stones in 61-86 years of age was higher,and the differences were statistically significant(all P<0.05).In different parts,the highest incidence of stone components are calcium oxalates.The incidence of uric acid stones in bladder was significantly higher than that in other parts,with statistical significance(all P<0.05).In different ages,the incidence of upper urinary tract stones is significantly higher than that of lower urinary tract stones.The incidence of bladder stones was the highest in 61-86 ages,and the differences were statistically significant(all P<0.05).Conclusions The main composition of urinary calculi in Wuxi area is calcium oxalate,with differences in gender,age and location.This study has important reference value for the clinical prevention and treatment of urinary calculi.

关 键 词：草酸钙 泌尿系结石 结石成分分析 无锡 

分 类 号：R691.4[医药卫生—泌尿科学]