新型磺酰基吲哚萘醌类化合物的合成及其光物理性质  

Synthesis and Photophysical Properties of Novel Sulfonyl Indolynaphthoquinones

作　　者：胥红 汪蓓 李福裕 肖瑶 黄东伟 王继宇[1,3] XU Hong;WANG Bei;LI Fuyu;XAO Yao;HUANG Dongwei;WANG Jiyu(Chengdu Institute of Organic Chemistry,Chinese Academy of Sciences,Chengdu 610041,China;University of Chinese Academy of Sciences,Beijing 100049,China;Department of Chemistry,Xihua University,Chengdu 610039,China)

机构地区：[1]中国科学院成都有机化学研究所,四川成都610041 [2]中国科学院大学,北京100049 [3]西华大学化学系,四川成都610039

出　　处：《合成化学》2024年第2期108-115,共8页Chinese Journal of Synthetic Chemistry

摘　　要：醌类化合物是一类具有独特生物活性和光物理性质的重要化合物。以吲哚萘醌和磺酰基肼为底物,经历碘化亚铜/过氧化叔丁醇介导的氧化自由基历程,简单、高效地以22%~67%的收率获得了8种取代的磺酰基醌类化合物(6a~6h),产物结构经过^(1)H NMR,^(13)C NMR和HR-MS(ESI)表征。初步探究了化合物6a~6h的光物理性质,结果表明:可以通过不同位置的取代基的变换来调节化合物的最大紫外吸收波长和荧光发射强度。Quinones are important compounds for the unique biological activity and photophysical properties.Here,eight substituted sulfonyl quinones(6a~6h)were synthesized in 22%~67%yields through cuprous iodide/tert-butyl peroxide mediated oxidation radical process with the use of indolinaphthoquinone and sulfonyl hydrazine,and the product structure is characterized by^(1)H NMR,^(13)C NMR and MS(ESI).The photophysical properties of compounds 6a~6h were investigated and the results showed the maximum UV absorption wavelength and fluorescence emission intensity of the compound can be adjusted by changing the substituents at different positions.

关 键 词：碘化亚铜/过氧化叔丁醇介导 氧化自由基反应 合成 磺酰基吲哚萘醌化合物 光物理性质 

分 类 号：O625[理学—有机化学]