猴痘病毒感染的神经系统表现研究进展  

Research advances in the neurological manifestations of monkeypox virus infection

作　　者：狄晓萌 刘磊(综述)[1] 王佳伟(审校)[1] DI Xiaomeng;LIU Lei;WANG Jiawei(Department of Neurology,Beijing Tongren Hospital,Capital Medical University,Beijing 102600,China)

机构地区：[1]首都医科大学附属北京同仁医院神经内科,北京100730

出　　处：《中风与神经疾病杂志》2024年第2期99-102,F0002,共5页Journal of Apoplexy and Nervous Diseases

摘　　要：在过去的一年内,猴痘的爆发已成为全球关注的问题。猴痘是猴痘病毒感染引起的人畜共患病,除典型的皮疹症状以外,猴痘病毒感染还可引起一系列神经系统表现,潜在的机制可能包括感染后免疫介导的神经系统损伤,以及病毒直接侵入神经系统。本文围绕猴痘病毒感染的神经系统表现进行综述,以促进早期识别、诊断猴痘病毒感染神经系统并发症,及时采取相应的防治措施。The outbreak of monkeypox has become a global matter of concern since last year.Monkeypox is a zoo‑notic disease caused by monkeypox virus(MPXV)infection,and in addition to the typical symptom of rash,MPXV infec‑tion can cause a series of neurological manifestations,with the potential mechanisms of immune-mediated neurological damage after infection and direct invasion of the virus into the nervous system.This article reviews the neurological mani‑festations of MPXV infection,so as to facilitate the early identification and diagnosis of the neurological complications of MPXV infection and adopt appropriate prevention and treatment measures in a timely manner.

关 键 词：猴痘病毒 神经系统 脑炎 急性播散性脑脊髓炎 疫苗 抗病毒药物 

分 类 号：R511[医药卫生—内科学] R535[医药卫生—临床医学] R512.3