非AIDS相关巨细胞病毒脑室脑炎1例报告  

Cytomegalovirus ventriculoencephalitis in patients without acquired immune deficiency syndrome:a case report

作　　者：李佳颐 有慧[3] 李享 范思远[1] 关鸿志[1] LI Jiayi;YOU Hui;LI Xiang(Department of Neurology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京协和医院神经科,中国医学科学院,北京100730 [2]北京协和医学院,中国医学科学院,北京100051 [3]北京协和医院放射科,中国医学科学院,北京100730 [4]清华大学医学院,北京100084

出　　处：《中风与神经疾病杂志》2024年第2期116-118,共3页Journal of Apoplexy and Nervous Diseases

基　　金：北京协和医院中央高水平医院临床科研专项基金(2022-PUMCH-B-120)。

摘　　要：巨细胞脑室脑炎是一种由巨细胞疱疹病毒(cytomegalovirus,CMV)感染室管膜与脑实质导致的严重脑炎,好发于免疫功能低下人群,主要见于AIDS患者,而在免疫正常的人群中神经系统感染极为罕见。我们报告1例非AIDS患者的巨细胞病毒脑室脑炎,本例患者以发热伴意识障碍起病,其增强磁共振成像呈现较典型的脑室脑膜的增强信号影,经过脑脊液CMV相关检查确诊,希望以此例非AIDS相关巨细胞病毒脑室脑炎为提高临床医生对于该疾病的认识提供帮助。Cytomegalovirus(CMV)ventriculoencephalitis is a type of severe encephalitis caused by CMV infection of the ependyma and brain parenchyma,with the main clinical manifestations of fever,headache,disturbance of con‑sciousness,and convulsions.The opportunistic infection of CMV often occurs in immunocompromised people,mainly in patients with acquired immune deficiency syndrome(AIDS),while nervous system infection is extremely rare in people with competent immune function.This article reports a case of CMV ventriculoencephalitis in a non-AIDS young male pa‑tient,with pyrexia and disturbance of consciousness as the initial presentation.Contrast-enhanced magnetic resonance im‑aging showed a typical enhanced signal shadow of the ventriculomeninges,and a confirmed diagnosis was made based on cerebrospinal fluid CMV examination.We hope that this case of non-AIDS-related CMV ventriculoencephalitis will pro‑vide help for clinicians to improve their understanding of the clinical and imaging manifestations of this disease.

关 键 词：巨细胞病毒 感染 脑室脑炎 磁共振成像 

分 类 号：R511[医药卫生—内科学] R512.3[医药卫生—临床医学]