紫色光合细菌LH1-RC复合物的结构生物学研究进展  

Advances in structural biology of photosynthetic core complexes in purple bacteria

作　　者：岳星宇 王征宇[3] 于龙江 YUE Xingyu;WANG Zhengyu;YU Longjiang(Key Laboratory of Photobiology,Institute of Botany,Chinese Academy of Sciences,Beijing 100093,China;University of Chinese Academy of Sciences,Beijing 100049,China;Faculty of Science,Ibaraki University,Mito 310-8512,Japan)

机构地区：[1]中国科学院植物研究所光生物学重点实验室,北京100093 [2]中国科学院大学,北京100049 [3]茨城大学理学部,日本水户310-8512

出　　处：《自然杂志》2024年第1期23-34,共12页Chinese Journal of Nature

基　　金：国家重点研发计划项目(2022YFC3401800);国家自然科学基金项目(32070264);中国科学院A类战略先导科技专项(XDA26050402)。

摘　　要：紫色光合细菌作为研究光合作用分子机制的一种古老的模式生物,通过无氧光合作用将太阳能转化为化学能,其光合作用原初反应主要发生在由捕光天线复合物1(LH1)及反应中心复合物(RC)组成的核心复合物(LH1-RC)中。近年来,随着晶体学和冷冻电镜技术的迅速发展,多个不同菌种来源的LH1-RC复合物的三维结构被解析出来,极大地拓展了人们对该复合物的认识。文章系统总结了近年来紫细菌光合膜蛋白复合物的结构生物学研究进展,为深入了解光合作用分子机制、提高光合效率、促进人工光合作用系统的开发及应用提供了理论基础。As an ancient model organism for studying molecular mechanisms of photosynthesis,purple bacteria convert solar energy into chemical energy through anoxygenic photosynthesis.The primary reaction of photosynthesis mainly occurs in the LH1-RC core complex,which is composed of light-harvesting antenna complex 1(LH1)and the reaction center(RC).Recently,structures of various bacterial LH1-RC complexes have been determined with developments of crystallography and cryo-EM techniques,significantly expanding our knowledge of this complex.In this paper,we systematically summarize the recent progress in structural biology research on the LH1-RC core complex from purple phototrophic bacteria,providing valuable insights for the deeper understanding of the molecular mechanisms of photosynthesis,improving photosynthetic efficiency,and advancing development and application of artificial photosynthetic systems.

关 键 词：光合作用 紫色光合细菌 捕光天线复合物 反应中心复合物 核心复合物 

分 类 号：Q945.11[生物学—植物学]