UVC技术灭活常见病原微生物研究现状及临床应用  

Research Status of UVC Technology Inactivation in Common Pathogenic Microorganisms

作　　者：吴明娥 周古翔 李振宇 李艳[1,2,4] 张雨驰 袁力蓉 吴荣谦[1,2,4] 吕毅 WU Minge;ZHOU Guxiang;LI Zhenyu;LI Yan;ZHANG Yuchi;YUAN Lirong;WU Rongqian;LV Yi(Shaanxi Province Center for Regenerative Medicine and Surgery Engineering Research,The First Affiliated Hospital of Xi’anJiaotong University,Xi’an Shaanxi 710061,China;National Local Joint EngineeringResearch Center for Precision Surgery&Regenerative Medicine,The First Affiliated Hospital of Xi’anJiaotong University,Xi’an Shaanxi 710061,China;.Hepatobiliary Surgery,The First Affiliated Hospital of Xi’anJiaotong University,Xi’an Shaanxi 710061,China;Shaanxi Provincial Key Laboratory of Magnetic Medicine,Xi’an Shaanxi710049,China;.Department of Medicine,Xi’an Jiaotong University,Xi’an Shaanxi 710061,China;Department of Telecommunications,Xi’an Jiaotong University,Xi’an Shaanxi 710061,China)

机构地区：[1]西安交通大学第一附属医院陕西省再生医学与外科工程研究中心,陕西西安710061 [2]西安交通大学第一附属医院精准外科与再生医学国家地方联合工程研究中心,陕西西安710061 [3]西安交通大学第一附属医院肝胆外科,陕西西安710061 [4]陕西省磁医学重点实验室,陕西西安710049 [5]西安交通大学医学部,陕西西安710061 [6]西安交通大学电信学部,陕西西安710061

出　　处：《中国医疗设备》2024年第2期10-15,共6页China Medical Devices

基　　金：陕西省重点研发计划(2021GXLH-Z-009)。

摘　　要：作为一种新型非抗生素治疗方法,波长范围为100~400 nm的紫外线已被证明具有一定的抗菌特性。不同波长紫外线的灭活效果存在差异,生物安全性也不尽相同。近年在这个领域涌现一批研究报道,尤其是波长范围为200~280 nm的C波段紫外线(Ultraviolet C,UVC)成为研究热点。本文对这一波长范围的研究新发现进行了综述,包括UVC灭活不同病原微生物的作用机制、影响因素及灭活效果,分析UVC技术的生物安全性,并简要归纳UVC技术设备在临床应用的研究进展,以期为相关研究提供参考。As a new non-antibiotic treatment method,ultraviolet in the wavelength range of 100-400 nm has been shown to have certain antibacterial properties.The sterilization effect varies from wavelength to wavelength of ultraviolet,and the biosafety also varies.In recent years,lots of research reports have emerged in this field,especially for ultraviolet C(UVC)in the wavelength range of 200-280 nm,which has become a hot research topic.This paper reviewed the new findings in this wavelength range,including the mechanism,factors and effectiveness of action of UVC inactivation of different pathogenic microorganisms,analyzed the biosafety of UVC technology,and also briefly summarized the research progress of UVC technical devices in clinical applications,aiming to provide a reference for related research.

关 键 词：C波段紫外线 非抗生素方法 病原微生物 生物安全性 

分 类 号：R197.39[医药卫生—卫生事业管理]