DSI Studio软件结合DTI在脑功能区肿瘤术后运动功能评估中的应用  

Application of DSI Studio Software Combined with DTI in Motor Function Evaluation of Postoperative Brain Functional Area Tumor

作　　者：高菲 牛光明[1] 陶胜忠[1] 刘展[1] 娄金峰[1] 王在斌 GAO Fei;NIU Guangming;TAO Shengzhong(Department of Neurosurgery,Second Affiliated Hospital of Zhengzhou University,Henan 450000,China)

机构地区：[1]郑州大学第二附属医院神经外科,450000

出　　处：《医学研究杂志》2024年第1期93-97,共5页Journal of Medical Research

基　　金：河南省医学教育研究项目(WJLX2020086)。

摘　　要：目的研究DSI Studio结合弥散张量成像(diffusion tensor imaging,DTI)应用于脑功能区肿瘤患者术后运动功能预后评估的价值。方法选择2018年1月~2022年8月于郑州大学第二附属医院行手术治疗且病理确诊的41例脑功能区肿瘤患者纳入研究。所有患者均完成3.0T磁共振成像常规序列及DTI检查,分别测量患侧及健侧内囊后肢皮质脊髓束(corticospinal tract,CST)投射区DTI参数,分析与患者MRC肌力评分及CST分级的相关性。结果患侧FA值明显低于健侧FA值(P<0.001),患侧ADC值明显高于健侧ADC值(P<0.001);患侧FA值、偏侧rFA值与CST分级呈负相关(P<0.01);ADC值、rADC值与CST分级呈正相关性(P<0.01);患侧FA值、偏侧rFA值与手术前后肌力评分程度呈正相关(P<0.01);ADC值、rADC值与CST分级呈负相关性(P<0.01);患者术前CST分级与对侧肌力呈负相关;患侧FA值,rFA值、ADC值、rADC值和CST分级受试者工作特征曲线下的面积分别是0.820(P<0.01)、0.796(P<0.01)、0.698(P<0.05)、0.638(P>0.05)、0.708(P<0.05)。结论DTI参数与肌力评分及CST分级对脑功能区肿瘤患者的术后运动功能预后的评估具有一定价值。Objective To study the value of DSI Studio combined with diffusion tensor imaging(DTI)in evaluating the prognosis of postoperative motor function in patients with brain functional area tumors.Methods From January 2018 to August 2022,41 patients with brain functional area tumors who underwent surgical treatment and were pathologically diagnosed in our hospital were included in the study.All patients completed 3.0 T MRI routine sequence and DTI examination.DTI parameters of the corticospinal tract(CST)projection area of posterior limb of the internal capsule on the affected side and the healthy side were measured respectively,and the correlation with MRC muscle strength score and the CST grade was analyzed.Results The FA value of the affected side was significantly lower than that of the healthy side(P<0.001),and the ADC value of the affected side was significantly higher than that of the healthy side(P<0.001).The FA value of the affected side and the lateral rFA value were negatively correlated with the CST grade(P<0.01).ADC value and rADC value were positively correlated with CST grade(P<0.01).The FA value of the affected side and the partial rFA value were positively correlated with the degree of muscle strength score before and after surgery(P<0.01).ADC value and rADC value were negatively correlated with CST grade(P<0.01).Preoperative CST grading was negatively correlated with contralateral muscle strength.The area under the ROC curve of FA value,rFA value,ADC value,rADC value,and CST grade were 0.820(P<0.01),0.796(P<0.01),0.698(P<0.05),0.638(P>0.05)and 0.708(P<0.05),respectively.Conclusion DTI parameters,muscle strength score and CST grade have certain value in the evaluation of postoperative motor function prognosis in patients with brain functional tumors.

关 键 词：弥散张量成像 脑功能区肿瘤 DSI STUDIO 运动功能 纤维束成像 皮质脊髓束 

分 类 号：R651[医药卫生—外科学]