女性压力性尿失禁伴膀胱活动低下治疗新进展  

Progression in the treatment of female stress urinary incontinence with underactive bladder

作　　者：梁子龙 宋逸凡 庞浩峰 吕继宗 武冠宇 邵永祥 孔令琛 庄宝琳 秦卫军 刘飞 LIANG Zilong;SONG Yifan;PANG Haofeng;LYU Jizong;WU Guanyu;SHAO Yongxiang;KONG Lingchen;ZHUANG Baolin;QIN Weijun;LIU Fei(Graduate Department,Xi'an Medical University,Xi'an 710021;Department of Urology,Xijing Hospital,School of Basic Medicine,Air Force Medical University,Xi'an 710032,China;Second Student Brigade,School of Basic Medicine,Air Force Medical University,Xi'an 710032,China)

机构地区：[1]西安医学院研究生工作部,陕西西安710021 [2]空军军医大学西京医院泌尿外科,陕西西安710032 [3]空军军医大学基础医学院学员二大队,陕西西安710032

出　　处：《现代泌尿外科杂志》2024年第2期183-186,共4页Journal of Modern Urology

基　　金：国家自然科学基金项目(No.81270844);西京医院学科助推计划(No.XJZT21L20,XJZT19Z30)。

摘　　要：压力性尿失禁(SUI)和膀胱活动低下症(UAB)均是女性下尿路功能障碍的常见类型,由于两者治疗机制相反,SUI合并UAB患者的治疗成为了临床棘手的问题。为提高对此类患者的诊疗水平,本文综述国内外UAB主要诊断标准并总结传统尿道中段悬吊术[耻骨后无张力尿道中段悬吊术(TVT)或经闭孔无张力尿道中段悬吊术(TOT)]和可调式尿道中段悬吊术[(经闭孔可调吊带(TOA)或Remeex系统]联合药物或间歇导尿的治疗经验,同时对干细胞注射、细胞因子疗法和基因治疗等前沿技术在此类患者的应用进行了展望,期望为临床医生和科研工作者提供参考。Stress urinary incontinence(SUI)and underactive bladder(UAB)are common types of lower urinary tract dysfunction in women.As the treatment mechanisms of the two conditions are contradictory,the treatment of SUI patients complicated with UAB remains a difficult clinical problem.In order to improve the treatment rate of such patients and promote research,this paper reviews the latest domestic and overseas diagnostic criteria of UAB,summarizes the treatment experience of conventional midurethral sling(tension-free vaginal tape or outside-in transobturator tape)and adjustable sling procedures(transobturator adjustable tape or Remeex system)combined with medication or intermittent catheterization,and the application prospects of cutting-edge technologies such as stem cell injection,cytokine therapy and gene therapy,so as to provide reference for clinicians and researchers.

关 键 词：女性 压力性尿失禁 膀胱活动低下 逼尿肌收缩功能低下 下尿路功能障碍 传统尿道中段悬吊术 可调式尿道中段悬吊术 

分 类 号：R695.1[医药卫生—泌尿科学]