2019年广州白云区医院监测点关于甲型流感和乙型流感流行情况分析  

Analysis of influenza A and influenza B epidemic in Baiyun district of Guangzhou in 2019

作　　者：许新强 李雪松 何伟业[1] 唐琼华[1] Xu Xinqiang;Li Xuesong;He Weiye;Tang Qionghua(Department of Clinical Laboratory,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China;The First Clinical College,Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China)

机构地区：[1]广州中医药大学第一附属医院检验科,广东广州510405 [2]广州中医药大学第一临床学院,广东广州510405

出　　处：《中华临床实验室管理电子杂志》2023年第4期230-234,共5页Chinese Journal of Clinical Laboratory Management(Electronic Edition）

摘　　要：目的分析广州白云区医院监测点2019年甲型和乙型流感的发病情况和流行季节,为流感的防治提供科学依据。方法收集广州中医药大学第一附属医院2019年1月至12月门诊部和住院部的流感检测资料。所有可疑流感患者均通过鼻咽拭子采样,利用胶体金试纸条同时对甲型和乙型流感病毒抗原进行检测,分析其阳性率、性别、年龄、实验室检查特征,并作统计分析。结果2019年全年共检测19827例疑似流感样本,门诊部17168例,全年阳性率19.1%,住院部2659例,全年阳性率3.0%;流感阳性患者主要集中在0~10岁年龄段和老年人群,11~20岁次之,男性与女性的流感阳性率差异无统计学意义(P=0.340)。在12个月中共有3个流感高峰期,分别在2019年的1~2月(甲型流感)、5~7月(甲型、乙型流感混合流行,乙型流感占优势),11~12月(甲型流感)。实验室检测指标中,2岁以上人群的流感阳性患者的WBC均值在正常范围内,而0~2岁人群则降低。中性粒细胞和单核细胞比例均值升高,淋巴细胞比例均值下降,CRP、血清淀粉样蛋白A均值高于正常范围值。结论2019年广州白云区流行性感冒呈现季节峰,冬、春、夏季流行,以甲型流感为主;流行性感冒好发于儿童、青少年和老年人群。Objective To analyze influenza A,B incidence and epidemic season,so as to provide a scientific basis for prevention of influenza.Methods To collect the outpatient and the inpatient flu detection data of The First Affiliated Hospital of Guangzhou University of Chinese Medicine in 2019 from January to December.All patients with suspected flu by nasopharyngeal swab sampling were detected A and B influenza virus antigen by colloidal gold strip,meanwhile analyze its positive features,gender,age,laboratory examination data.Results 19827 cases of flu samples were detected in 2019 including 17168 cases of outpatient samples and 2659 cases of inpatient samples.The outpatient and the inpatient positive rate were 19.1%and 3.0%respectively.Influenza mainly concentrated in the aged 0 to 10 and the elder,followed by 11~20 years old,and the flu positive rate of men and women had no statistical difference(P=0.340).The epidemic situation of influenza was the characteristic of three peaks,which were from January to February(influenza A),May to July(influenza A and B mixed popular,influenza B advantage),November and December(influenza A).2 years of age or older population of flu patients with positive WBC count the mean absolute value within the normal range,lowering 0~2 years old group.Average proportion of neutrophils and monocytes elevated,but lymphocyte percentage average reduced;C-reactive protein,serum amyloid A protein average value was higher than the normal range.Conclusions The characteristic of influenza outbreak in Baiyun district of Guangzhou showed seasonal peak in 2019,which influenza A popular in winter,spring and summer.Children,adolescents and the elderly were at high risk for the outbreak of influenza.

关 键 词：流感病毒 甲型流感 乙型流感 

分 类 号：R511.7[医药卫生—内科学]