基于Eclipse计划系统在左侧乳腺癌术后RapidArc与dIMRT放疗技术剂量学对比研究  

Dosimetric comparative study of RapidArc and dimrt radiotherapy technology in patients with left breast cancer after surgery based on eclipse planning system

作　　者：陈荣耀 胡俊峰[1] Chen Rongyao;Hu Junfeng(School of Mechanical and Electrical Engineering,Jiangxi University of Science and Technology,Ganzhou 341000,China)

机构地区：[1]江西理工大学机电工程学院,赣州341000

出　　处：《现代仪器与医疗》2023年第6期75-80,86,共7页Modern Instruments & Medical Treatment

摘　　要：目的比较左侧乳腺癌术后旋转容积弧形调强放射治疗(RapidArc)计划和固定野动态调强(dIMRT)放疗计划方式在剂量学上的差异。方法20例左侧乳腺癌术后患者基于Eclipse系统分别采用RapidArc及dIMRT计划方式,对比靶区剂量、危及器官保护的差异。结果RapidArc计划V95及V105显著低于dIMRT计划,差异有统计学意义(P<0.05)。患侧肺剂量分布上,RapidArc的V5,V30显著高于dIMRT,差异有统计学意义(P<0.05)。RapidArc的V20低于dIMRT,差异有统计学意义(P<0.05)。健侧肺剂量分布上,RapidArc的D_(mean)、V5、V10显著高于dIMRT,差异有统计学意义(P<0.05)。健侧乳腺剂量分布上,RapidArc的D_(mean)、V5、V10显著高于dIMRT,差异有统计学意义(P<0.05)。心脏剂量分布上,RapidArc的D_(mean)低于dIMRT,差异有统计学意义(P<0.05)。而V20、V30显著高于dIMRT,差异有统计学意义(P<0.05)。在总机器跳数MU(Machine unit)和治疗时间T(time)比较中,RapidArc和dIMRT两种计划方式的MU,差异有统计学意义(P<0.05)。RapidArc计划MU明显低于dIMRT,治疗时间也明显较短。结论RapidArc和dIMRT均能满足靶区及危及器官的临床要求,RapidArc相比dIMRT在治疗中可以提供更加平滑、均匀和精确的剂量分布,从而提高治疗效果并减少副作用。dIMRT在剂量分布方面具有更大的灵活性和精确性,RapidArc则更加高效和快速。Objective This study aims to compare the dosimetric differences between RapidArc(volume intensity modulated arc therapy)radiotherapy planning and dIMRT(fixed field dynamic intensity modulated radiotherapy)radiotherapy planning after left breast cancer surgery.Methods RapidArc and dIMRT planning methods were used in 20 patients with left side breast cancer after operation based on Eclipse system to compare the difference of target dose and organ protection at risk.Results The V95 and V105 of RapidArc plan were significantly lower than those of dIMRT plan,with statistical significance(P<0.05).In the dose distribution of the affected lung,the V5 and V30 of RapidArc were significantly higher than those of dIMRT,with statistical significance(P<0.05).The V20 of RapidArc was lower than that of dIMRT,and the difference was statistically significant(P<0.05).In the dose distribution of healthy lung,D_(mean),V5 and V10 of RapidArc were significantly higher than those of dIMRT,with statistical significance(P<0.05).In the dose distribution of the healthy breast,D_(mean),V5 and V10 of RapidArc were significantly higher than those of dIMRT,with statistical significance(P<0.05).In cardiac dose distribution,the D_(mean) of RapidArc was lower than that of dIMRT(P<0.05).V20 and V30 were significantly higher than dIMRT,the difference was statistically significant(P<0.05).In the comparison of total Machine u⁃nit MU(Machine unit)and treatment time T(time),there was a statistically significant difference between RapidArc and dIMRT(P<0.05).The RapidArc program MU was significantly lower than dIMRT,and the treatment time was also significantly shorter.Conclu⁃sion Both RapidArc and dIMRT can meet the clinical requirements of target areas and organs at risk.RapidArc can provide a smoot⁃her,more uniform and accurate dose distribution than dIMRT in treatment,so as to improve the therapeutic effect and reduce side effects.Dimrt has greater flexibility and accuracy in dose distribution,while RapidArc is more efficient and fast.

关 键 词：Eclipse系统 左侧乳腺癌 术后放疗 dIMRT RAPIDARC 剂量学 

分 类 号：TH774[机械工程—仪器科学与技术] R738.1[机械工程—精密仪器及机械]