早期经口营养及经鼻空肠管营养应用于中重度急性胰腺炎的疗效对比  

Comparison of the therapeutic Effects of early oral nutrition and nasal-jejunal nutrition in the Treatment of moderate to severe acute Pancreatitis

作　　者：姬旭慧[1] 周燕[1] 吕全军 JI Xuhui;ZHOU Yan;LYU Quanjun(Department of Clinical Nutrition,Zhengzhou Second People's Hospital,Zhengzhou Henan 450006,China;Department of Clinical Nutrition,Zhengzhou University First Affiliated Hospital,Zhengzhou Henan 450006,China)

机构地区：[1]郑州市第二人民医院临床营养科,河南郑州450006 [2]郑州大学第一附属医院临床营养科,河南郑州450000

出　　处：《临床研究》2024年第3期21-23,共3页Clinical Research

摘　　要：目的对比早期经口营养及经鼻空肠管营养应用于中重度急性胰腺炎的疗效。方法选择郑州市第二人民医院2020年5月至2023年5月收治的中重度急性胰腺炎患者90例,按随机数字表法分成对照组和观察组,各45例。对照组予以经鼻空肠管营养治疗,观察组予以早期经口营养治疗,比较两组开始进食半流质食物时间、住院时间、住院费用、肠内营养相关并发症发生率、腹腔感染率、病死率、营养指标和感染指标。结果两组开始进食半流质食物时间,住院时间,腹腔感染率,病死率,治疗1 d、7 d、14 d前白蛋白、白细胞计数值,治疗1 d、7 d白蛋白、C反应蛋白计数值比较,差异无统计学意义(P>0.05);观察组住院费用、肠内营养相关并发症发生率、治疗14 d CRP值显著低于对照组,治疗14 d白蛋白高于对照组,差异均有统计学意义(P<0.05)。结论早期经口营养在中重度急性胰腺炎治疗中优于经鼻空肠管营养,可以降低患者肠内营养相关并发症发生率,改善肠内营养和感染指标,减少患者住院费用,提高患者生活质量,值得临床借鉴。Objective To compare the therapeutic effects of early oral nutrition and nasal-jejunal nutrition on moderate to severe acute pancreatitis.Methods A total of 90 patients with moderate to severe acute pancreatitis admitted to the Second People's Hospital of Zhengzhou from May 2020 to May 2023 were divided into control group and observation group using a random number table method,with 45 cases in each group.The control group received nasal-jejunal nutrition treatment,while the observation group received early oral nutrition treatment.The start time of eating,hospitalization time,hospitalization costs,incidence of enteral nutrition related complications,abdominal infection rate,mortality rate,nutritional indicators,and infection indicators were compared between the two groups.Results There was no statistically significant difference(P>0.05)between the two groups in terms of starting eating time,hospitalization time,abdominal infection rate,mortality rate,albumin and white blood cell counts before treatment for 1,7,and 14 days,as well as albumin and C-reactive protein counts after treatment for 1 and 7 days;The hospitalization cost,incidence of enteral nutrition related complications,and CRP value after 14 days of treatment of the observation group were significantly lower than those of the control group,while albumin levels were higher than those of the control group after 14 days of treatment,with statistical significance(P<0.05).Conclusion Early oral nutrition is superior to nasal jejunal nutrition in the treatment of moderate to severe acute pancreatitis,which can reduce the incidence of complications related to enteral nutrition,improve enteral nutrition and infection indicators,reduce hospitalization costs,and improve patient quality of life.It is worth clinical reference.

关 键 词：急性胰腺炎 中重度 早期经口营养 经鼻空肠管营养 

分 类 号：R657.51[医药卫生—外科学]