辅助生殖技术与产后母乳喂养结局关系的Meta分析  

Meta-analysis of correlation between assisted reproductive technology and postpartum breastfeeding outcomes

作　　者：宋丹妮 周晖[2] 张莹莹[1] 蒲丛珊 姜微微 张佳华 赵纯[3] 单春剑[1] Song Danni;Zhou Hui;Zhang Yingying;Pu Congshan;Jiang Weiwei;Zhang Jiahua;Zhao Chun;Shan Chunjian(Department of Obstetrics,Women's Hospital of Nanjing Medical University(Nanjing Women and Children's Healthcare Hospital),Nanjing 210004,China;Nursing Department,Women's Hospital of Nanjing Medical University(Nanjing Women and Children's Healthcare Hospital),Nanjing 210004,China;Reproductive center,Women's Hospital of Nanjing Medical University(Nanjing Women and Children's Healthcare Hospital),Nanjing 210004,China)

机构地区：[1]南京医科大学附属妇产医院(南京市妇幼保健院)产科,南京210004 [2]南京医科大学附属妇产医院(南京市妇幼保健院)护理部,南京210004 [3]南京医科大学附属妇产医院(南京市妇幼保健院)生殖中心,南京210004

出　　处：《中华现代护理杂志》2024年第3期322-330,共9页Chinese Journal of Modern Nursing

基　　金：国家自然科学基金面上项目(81971386);江苏省妇幼保健协会科研课题(FYX202111)。

摘　　要：目的评价辅助生殖技术(ART)对产后母乳喂养结局的影响。方法计算机检索中国生物医学文献数据库、中国知网、维普网、万方数据库、PubMed、Embase、Web of Science、Cochrane Library,检索时限为建库至2023年3月15日,由2名研究者独立进行文献检索、筛选、资料提取及质量评价后,采用R 4.2.2软件进行Meta分析。结果共纳入11篇文献。Meta分析结果显示,与自然受孕产妇相比,ART受孕产妇产后1周纯母乳喂养率(RR=0.84,95%CI:0.73~0.97)、产后6个月纯母乳喂养率(RR=0.77,95%CI:0.61~0.98)、产后母乳喂养时长>6个月的发生率(RR=0.71,95%CI:0.53~0.96)均有所降低,产后12个月人工喂养率(RR=1.09,95%CI:1.02~1.17)增加,但在产后8个月人工喂养率、产后母乳喂养时长>12个月的发生率、母乳喂养困难发生率方面比较,差异无统计学意义(P>0.05)。结论ART治疗降低了产妇产后1周、6个月纯母乳喂养率、产后母乳喂养时长>6个月的发生率,增加了产后12个月人工喂养率,但对母乳喂养困难发生率的影响尚不明确,仍需更多高质量的研究进一步论证。Objective To evaluate the impact of assisted reproductive technology(ART)on postpartum breastfeeding outcomes.Methods This paper electronically retrieved the China Biology Medicine disc,China National Knowledge Infrastructure,VIP,WanFang Data,PubMed,Embase,Web of Science,and Cochrane Library.The search period was from database establishment to March 15,2023.After independent literature search,screening,data extraction,and quality evaluation by two researchers,Meta-analysis was conducted using R 4.2.2 software.Results A total of 11 articles were included.Meta-analysis showed that compared with naturally conceived mothers,the rates of exclusive breastfeeding at 1th week postpartum(RR=0.84,95%CI:0.73-0.97),exclusive breastfeeding at 6th months postpartum(RR=0.77,95%CI:0.61-0.98),and the incidence of breastfeeding for>6 months postpartum(RR=0.71,95%CI:0.53-0.96)were decreased,and the rate of artificial feeding at 12th months postpartum(RR=1.09,95%CI:1.02-1.17)was increased.However,there were no statistically significant differences in the rate of artificial feeding at 8th months postpartum,the incidence of breastfeeding duration>12 months,and the incidence of breastfeeding difficulties(P>0.05).Conclusions ART reduces the rate of exclusive breastfeeding in postpartum 1th week and 6th months,and the incidence of postpartum breastfeeding duration>6 months,and increases the artificial feeding rate in postpartum 12th months.However,the impact of ART on the incidence of breastfeeding difficulties is not yet clear and still needs to be further demonstrated by high-quality studies.

关 键 词：母乳喂养 辅助生殖技术 母乳喂养困难 META分析 

分 类 号：R714.8[医药卫生—妇产科学]