血液透析暴发性感染的流行病学特征和调查表的构建  

Construction of investigation form for hemodialysis infection outbreak based on epidemiological characteristics

作　　者：曹煜隆 单娇 王琰[3] 怀伟[4] 包小源[5] 金梦[5] 匡季秋[1] 高燕[1] CAO Yulong;SHAN Jiao;WANG Yan;HUAI Wei;BAO Xiaoyuan;JIN Meng;KUANG Jiqiu;GAO Yan(Department of Hospital-Acquired Infection Control,Peking University People's Hospital,Beijing 100044,China;Department of Hospital-Acquired Infection Control,Beijing Jishuitan Hospital,Beijing 100035,China;Department of Nephrology,Peking University Peoples Hospital,Beijing 100044,China;Department of Emergency,Peking University Third Hospital,Beijing 100191,China;Medical Informatics Center,Peking University,Beijing 100191,China)

机构地区：[1]北京大学人民医院感染管理-疾病预防控制处,北京100044 [2]北京积水潭医院院感处 [3]北京大学人民医院肾内科 [4]北京大学第三医院急诊科 [5]北京大学医学信息学中心

出　　处：《肾脏病与透析肾移植杂志》2023年第6期546-550,共5页Chinese Journal of Nephrology,Dialysis & Transplantation

基　　金：国家临床重点专科能力建设项目经费资助;北京市临床重点专科能力建设项目经费资助;国家卫生健康委医院管理研究所“感·动中国”医疗机构感染预防与控制科研项目(GY2023044);北京大学人民医院研究与发展基金资助课题(RDM2021-02)。

摘　　要：目的:建立血液透析(HD)感染暴发个案调查表单,以期在感染聚集的早期探寻感染来源,防止感染暴发。方法:在研究HD感染暴发事件后,我们进行数据提取与标注,之后进行了两轮专家咨询,综合考虑15位专家的意见和建议,采用德尔菲法确定感染暴发可能来源。结果:共有87项HD感染暴发的研究符合纳入条件。权威系数(Cr)均值为0.850。专家咨询两轮后的协调系数(Kendall’s W)为0.351(P<0.005),显示专家意见共识性较好。根据HD感染暴发来源的4个主要项目和13个次要项目,以及感染患者的三间分布特征,构建个案调查表单。结论:该调查表可用于在HD感染聚集事件的早期调查,为识别感染潜在来源提供参考,但其外部适用性有待进一步评估。Objective:To develop an investigation form for hemodialysis infection outbreak,and identify sources of the outbreak in the early stage.Methodology:After an exhaustive literature review,we used the Delphi method to determine the indicators and relative risk scores of the assessment tools through two rounds of specialist consultation and overall consideration of the opinions and suggestions of 15 specialists.Results:A total of 87 studies of hemodialysis infection outbreak were eligible for inclusion.The mean of authority coefficient(Cr)was 0.850.Kendall\s W coefficient of the specialist consultation was 0.351 after two rounds of consultation(P<0.005),suggesting that the specialists had similar opinions.Based on 4 primary items and 13 secondary items of the source of hemodialysis infection outbreak,and tripartite distribution characteristics of infected patients,we constructed the investigation form.Conclusion:The investigation form can be used in the early stage of cluster of investigation of hemodialysis infection clusters to provide a reference for identifying potential sources of infection,However,the external applicability of the form needs to be further evaluated.

关 键 词：血液透析感染暴发 调查表单 感染来源 

分 类 号：R692.5[医药卫生—泌尿科学]