伏马菌素B_(1)脱毒研究进展  

Research Progress on Detoxification of Fumonisin B_(1)

作　　者：李露露[1] 王硕[1] 王晓萱 龙淼[1] LI Lulu;WANG Shuo;WANG Xiaoxuan;LONG Miao(Key Laboratory of Ruminant Infectious Disease Prevention and Control(East),Ministry of Agriculture and Rural Affairs,Key Laboratory of Livestock Infectious Diseases,Ministry of Education,College of Animal Science and Medicine,Shenyang Agricultural University,Shenyang 110161,China)

机构地区：[1]沈阳农业大学动物科学与医学学院,重要家畜疫病研究教育部重点实验室,农业农村部反刍动物重大疫病防控重点实验室(东部),沈阳110161

出　　处：《动物营养学报》2024年第1期115-123,共9页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金(32273074,31972746,31872538,31772809);辽宁省教育厅重点项目(LJKZ0632)。

摘　　要：伏马菌素B_(1)(FB_(1))是由镰刀菌产生的水溶性代谢产物,存在于镰刀菌污染了的谷物、油料作物、坚果、饲草和饲料中,是常见的真菌毒素之一。FB_(1)会对神经系统、呼吸系统、消化系统和生殖系统产生不同毒性作用,给农牧业造成不可估量的经济损失。如何对FB_(1)进行脱毒,以降低其毒性作用,是目前研究的热点。因此,本文对FB_(1)的物理脱毒、化学脱毒、生物脱毒及其应用进行综述,重点对常用于FB_(1)生物脱毒的菌株和酶及其脱毒效果、脱毒机制进行了深入探讨,以期为提高FB_(1)脱毒效率和开发新的FB_(1)脱毒方法提供参考和思路。Fumonisin B_(1)(FB_(1))is a water-soluble metabolite produced by Fusarium oxysporum,which is one of the prevalent mycotoxins,naturally occurring in cereals,oilseed crops,nuts,forage and feedstuffs.FB_(1) exposure can produce different toxic effects on the nervous system,respiratory system,digestive system and reproductive system,causing immeasurable economic losses in global agriculture and animal husbandry.The current research focus lies in the detoxification of FB_(1) and mitigation of its toxic impact.Therefore,this article comprehensively reviewed the physical,chemical,biological methods and applications of FB_(1) detoxification.With a particular focus on the strains and enzymes commonly used for FB_(1) biodetoxification,as well as their detoxification effects and mechanisms,a thorough and detailed discussion was pursued,aiming to provide reference and ideas for improving the detoxification efficiency of FB_(1) and developing a new FB_(1) detoxification method.

关 键 词：伏马菌素B_(1) 饲料 脱毒 微生物 酶 

分 类 号：S816[农业科学—饲料科学]