新型冠状病毒XBB变异株研究进展  

Progress of research on SARS-CoV-2 XBB variant strain

作　　者：马思旻 赖晓全 谭昆 MA Si-min;LAI Xiao-quan;TAN Kun(Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院医院感染管理科,湖北武汉430030

出　　处：《中华医院感染学杂志》2024年第2期304-309,共6页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(82204871)。

摘　　要：随着新型冠状病毒(SARS-CoV-2)不断进化和变异,相继出现多种变异株。XBB变异株于2022年8月13日首次在印度发现,具有传播快、适应性强、免疫逃避等特点,逐渐成为全球主要流行毒株。本文就XBB变异株的致病性、流行特征、免疫逃逸特性和现今疫苗效果等进行总结并对未来应对XBB的防控方式提出建议。As the severe acute respiratory syndrome corona-virus 2(SARS-CoV-2)continues to evolve and mutate,a variety of variant strains have emerged.XBB variant strains were firstly discovered in India on August 13,2022 and have displayed the characteristics of rapid transmission,strong adaptability and immune evasion,and the vari-ant strains have gradually become the most prevalent around the world.The pathogenicity,epidemiological char-acteristics and features of immue escape of the XBB variant strains as well as the effect of vaccines were summa-rized in the article,and coping measures for prevention and control of the XBB strains were proposed.

关 键 词：XBB 致病性 流行特征 免疫逃逸 疫苗效果 防控措施 

分 类 号：R373[医药卫生—病原生物学]