人偏肺病毒感染研究进展  

Progress of research on human metapneumovirus infection

作　　者：傅家祺 蒋荣猛[2] FU Jia-qi;JIANG Rong-meng(Peking University,Beijing 100015,China;不详)

机构地区：[1]北京大学医学部,北京100015 [2]首都医科大学附属北京地坛医院感染中心,北京100015

出　　处：《中华医院感染学杂志》2024年第2期310-314,共5页Chinese Journal of Nosocomiology

基　　金：2022年北京市高层次公共卫生技术人才建设项目(学科带头人-01-02)。

摘　　要：人偏肺病毒属于副粘病毒科,肺病毒亚科,偏肺病毒属,为有包膜的单链负RNA病毒。能够引起各年龄段人群感染,多表现为轻度自限性疾病。在免疫功能低下人群中可进展为重症肺炎、多器官功能衰竭,甚至导致死亡。主要通过呼吸道和接触传播,主要依靠核酸检测确诊,无特异性的抗病毒药物,主要以支持治疗为主。尚无疫苗上市。Human metapneumovirus,a single stranded negative RNA virus with an envelope,belongs to the family Pa-ramyxoviridae,subfamily Pneumoviruses,and genus Polypneumovirus.It often causes infections among the population of all age groups,most of the population manifest as mild self-limiting diseases,which may progress to severe pneumonia,multiple organ failure and even lead to death among the immunocompromised population.The respiratory tract and con-tact were the major transmission routes,nucleic acid test was the major diagnostic mean.There are no specific antiviral drugs,and supportive treatment is dominant.There has not been vaccine available yet.

关 键 词：人偏肺病毒 感染 病原学 流行病学 发病机制 临床表现 诊断和治疗 

分 类 号：R373[医药卫生—病原生物学]