自拟利胆经验方治疗慢性胆囊炎临床观察  

Gallbladder-relievingg Empirical Recipe in Treating Chronic Cholecystitis

作　　者：谢波[1] 黄海[2] 孙晓生[3] XIE Bo;HUANG Hai;SUN Xiaosheng(Department of Teaching,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Province,Guangzhou 510405,China;The Second Clinical College,Guangzhou University of Chinese Medicine,Guangdong Province,Guangzhou 510405,China;Department of Preventive Treatment of Disease,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Province,Guangzhou 510405,China)

机构地区：[1]广州中医药大学第一附属医院教学处,广东广州510405 [2]广州中医药大学第二临床医学院,广东广州510405 [3]广州中医药大学第一附属医院治未病科,广东广州510405

出　　处：《光明中医》2024年第2期222-226,共5页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：国家中医药管理局孙晓生全国名老中医药专家传承工作室建设项目(No.国中医药人教函[2022]75号)。

摘　　要：目的观察孙晓生教授自拟利胆1号方治疗慢性胆囊炎的临床疗效和安全性。方法选取108例慢性胆囊炎患者为研究对象,利用随机数字表法分为2组,各54例。对照组采取常规西医治疗,观察组加用自拟利胆1号方治疗,4周后对比2组临床疗效。结果治疗前2组患者的中医症状积分、肝胆功能指标、免疫指标、炎性细胞因子相比,组间差异无统计学意义(P>0.05),治疗4周后均较治疗前改善且观察组改善效果优于对照组(P<0.05);观察组不良反应发生率与对照组相比,差异无统计学意义(P>0.05)。结论自拟利胆1号方对慢性胆囊炎有效,不良反应发生率低,使用前景广阔。Objective To observe the clinical efficacy and safety of Professor Sun Xiaosheng's self-made Lidan No.1 prescription in the treatment of chronic cholecystitis.Methods A total of 108 patients with chronic cholecystitis were selected as the research objects,and were divided into two groups by random number table method,with 54 cases in each group.The control group was treated with conventional Western medicine,and the observation group was treated with self-made Lidan No.1 Recipe.After 4 weeks,the difference in clinical efficacy between the two groups was compared.Results Before treatment,there was no significant difference in TCM syndrome score,liver and bile function index,immune index and inflammatory cytokine between 2 groups(P>0.05).After 4 weeks of treatment,the indexes of 2 groups were improved compared with before treatment,and the improvement effect of observation group was better than that of control group(P<0.05).The incidence of nausea/vomiting,rash and diarrhea/abdominal pain in the observation group,which were not significantly different from in the control group(P>0.05).Conclusion The self-made Lidan No.1 recipe helps to further improve the clinical efficacy of patients with chronic cholecystitis.The incidence of adverse reactions is low,and it has broad prospects for promotion and use.

关 键 词：胆胀 慢性胆囊炎 自拟利胆1号方 肝胆功能 孙晓生 

分 类 号：R259[医药卫生—中西医结合]