富血小板血浆在软骨、肌腱及骨组织损伤抗炎修复中应用的研究进展  

Progress of research on application of platelet rich plasma in anti-inflammation and repair of cartilage,tendon and bone tissue injuries

作　　者：张洪禹 于栀子 甘阳[1] ZHANG Hong-yu;YU Zhi-zi;GAN Yang(Wuzhou University,School of Sports and Health,Wuzhou,Guangri 543002,China;不详)

机构地区：[1]梧州学院体育健康学院,广西梧州543002 [2]阿荣旗人民医院麻醉科,内蒙古呼伦贝尔162700

出　　处：《中华医院感染学杂志》2024年第1期156-160,共5页Chinese Journal of Nosocomiology

基　　金：中国博士后科学基金面上项目(2020M673663)。

摘　　要：软骨、肌腱及骨组织损伤是骨科及运动医学科常见疾病。富血小板血浆(PRP)含有多种高浓度生长因子和介质。通过离心浓缩,将PRP注射到损伤部位,可以提高骨、软骨及其他软组织的自愈能力。PRP制剂治疗骨、软骨及其他软组织损伤已成为当今研究热点。同时,因PRP含有大量血小板、高浓度的白细胞和多种抗菌肽,有望成为预防术后感染、治疗慢性伤口及预防植入物相关感染的有效补充剂。为了评估PRP制剂对不同骨、软骨及其他软组织损伤的治疗效果,结合最近新发布的RPR相关专家共识,本文就相关研究进展作一综述。Cartilage,tendon and bone tissue injuries are common diseases for orthopedics and sport medicine.Platelet rich plasma(PRP)contains various types of high concentrations of growth factors and mediators.Centri-fuged and concentrated PRP was injected into to injured sites,which may facilitate the self-healing.The treatment of bone,cartilage and other soft tissue injuries with PRP has become a research hotspot.PRP is supposed to be an effective supplement for prevention of postoperative infection,treatment of chronic wounds and prevention of im-plant-associated infection due to its containing with a large number of platelets,high concentrations of white blood cells and a variety of antimicrobial peptides.In combination with the latest issued PRP-related expert consensuses,the effect of PRP on treatment of the bone,cartilage and other soft tissue injuries was evaluated in the review arti-cle.

关 键 词：富血小板血浆 关节软骨损伤 韧带损伤 肌腱损伤 骨折 抗感染 

分 类 号：R683[医药卫生—骨科学]