HPV拓展基因分型检测在宫颈癌预防中的临床价值  

Clinical Value of HPV Extended Genotyping Test in Cervical Cancer Prevention

作　　者：王嫱 宋殿荣[2] WANG Qiang;SONG Dianrong(Graduate School,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Department of Gynecology,the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300250,China)

机构地区：[1]天津中医药大学研究生院,天津301617 [2]天津中医药大学第二附属医院妇科,天津300250

出　　处：《医学综述》2024年第4期502-507,共6页Medical Recapitulate

摘　　要：人乳头瘤病毒(HPV)感染是导致宫颈病变的主要原因,以HPV检测为初筛是宫颈癌筛查的进步。HPV检测特异性低,基于HPV的筛查可能面临很多挑战。HPV拓展基因分型检测通过检测HPV基因型可更早预测持续性宫颈病变的风险,有助于提前采取预防和治疗干预措施,以减少相关疾病的发生,还可有效地区分低风险与高风险患者,以最大限度地优化医疗资源分配。早期进行HPV拓展基因分型检测是宫颈病变未来风险预测和分层的关键,其在宫颈癌预防中具有重要价值。Human papillomavirus(HPV)infection is the main cause of cervical lesions,and HPV testing as the initial screening is an advancement in cervical cancer screening.The specificity of HPV detection is low,and HPV based screening may face many challenges.The HPV extended genotyping test can predict the risk of persistent cervical lesions earlier by detecting the HPV genotype,which helps to take preventive and therapeutic interventions in advance to reduce the occurrence of related diseases.It can also effectively distinguish the low-risk and high-risk patients to maximize the allocation of medical resources.Early detection of HPV extended genotype is crucial for predicting and stratifying the future risk of cervical lesions,and it has a great value in the prevention of cervical cancer.

关 键 词：宫颈癌 人乳头瘤病毒 人乳头瘤病毒拓展基因分型 

分 类 号：R711.74[医药卫生—妇产科学]