健康成年女性腰椎骨髓成分对DWI骨髓扩散信号强度及ADC值的影响  

Effect of lumbar bone marrow composition on bone marrow diffusion signal intensity and apparent diffusion coefficient in healthy adult women

作　　者：韩铮 胡亮 潘江峰[1] 夏秀梅 HAN Zheng;HU Liang;PAN Jiangfeng;XIA Xiumei(Department of Medical Imaging,Jinhua Municipal Central Hospital,Jinhua,Zhejiang 321000,China)

机构地区：[1]金华市中心医院医学影像科,浙江金华321000

出　　处：《重庆医学》2024年第4期555-559,共5页Chongqing medicine

基　　金：浙江省金华市科学技术局公益类项目(2021-4-033);金华市中心医院中青年科研启动基金(JY2019-2-14)。

摘　　要：目的分析健康成年女性腰椎骨髓成分对骨髓扩散加权成像(DWI)表现的影响。方法回顾性分析103名成年女性上腹部MRI检查内容,根据两点法水脂分离技术测量腰1椎体骨髓脂肪分数,根据DWI测量腰1椎体表观扩散系数(ADC)值,基于DWI(b=800 s/mm 2)图像,根据腰1椎体与邻近竖脊肌信号强度比较将研究对象分为高信号组(n=51)和等低信号组(n=52)。分析年龄、腰椎骨髓脂肪分数、月经状况对腰椎骨髓扩散信号强度及ADC值的影响。最后分析腰椎骨髓脂肪分数与ADC值间的相关性。结果单因素分析表明,健康成年女性腰椎骨髓扩散信号强度及ADC值受年龄、腰椎骨髓脂肪分数和月经状况的影响(P<0.001)。多因素分析表明,年龄(P=0.046)和腰椎骨髓脂肪分数(P=0.005)是腰椎骨髓扩散信号强度的影响因素,而月经状态(P=0.242)不是其影响因素。另外,腰椎骨髓脂肪分数(P<0.001)是腰椎骨髓ADC值的影响因素,两者呈负相关(r=-0.607,P<0.001),而年龄(P=0.497)和月经状态(P=0.082)不是其影响因素。结论健康成年女性腰椎骨髓成分对骨髓扩散信号强度及ADC值有明显影响。Objective To analyze the effect of lumbar bone marrow composition on bone marrow diffusion-weighted imaging(DWI)in healthy adult women.Methods Retrospective analysis was performed on upper abdominal MRI of 103 adult women.Bone marrow fat fraction of lumbar vertebra was measured according to two-point water-lipid separation technique,and apparent diffusion coefficient(ADC)value of lumbar vertebra was measured according to DWI image(b=800 s/mm2).The subjects were divided into the high-signal group and the equal-low-signal group according to the signal intensity of lumbar vertebra and adjacent erector spine muscles.The effects of age,lumbar bone marrow fat fraction and menstrual status on the signal intensity and ADC value of lumbar bone marrow diffusion were analyzed.Finally,the correlation between lumbar bone marrow fat fraction and ADC value was analyzed.Results Univariate analysis showed that the lumbar bone marrow diffusion signal intensity and ADC value were affected by age,lumbar bone marrow fat fraction and menstrual status(P<0.001).Multivariate analysis showed that age(P=0.046)and lumbar bone marrow fat fraction(P=0.005)were the influencing factors of lumbar bone marrow diffusion signal intensity,but menstrual status(P=0.242)was not the influencing factor.In addition,lumbar bone marrow fat fraction(P<0.001)was the factor influencing the ADC value of lumbar bone marrow,and the two were negatively correlated(r=-0.607,P<0.001),but age(P=0.497)and menstrual status(P=0.082)were not the influencing factors.Conclusion The bone marrow composition of lumbar vertebrae in healthy adult women has significant effects on the signal intensity and ADC value of bone marrow diffusion.

关 键 词：腰椎骨髓 扩散加权成像 年龄 脂肪分数 月经状况 

分 类 号：R445.2[医药卫生—影像医学与核医学]