右美托咪定与咪达唑仑在小儿手术麻醉中的应用效果比较  

Comparison of application effect between Dexmedetomidine and Midazolam in pediatric surgical anesthesia

作　　者：孙玉玲 SUN Yuling(Department of Anesthesiology,the Third People’s Hospital of Chengyang District,Qingdao,Shandong Province,Qingdao 266107,China)

机构地区：[1]青岛市城阳区第三人民医院麻醉科,山东青岛266107

出　　处：《妇儿健康导刊》2024年第3期111-113,117,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：目的比较右美托咪定与咪达唑仑在小儿手术麻醉中的应用效果。方法选取2020年2月至2023年8月青岛市城阳区第三人民医院麻醉科收治的90例手术麻醉患儿作为研究对象,按照随机数字表法将其分为对照组(45例)与研究组(45例)。对照组采用咪达唑仑麻醉,研究组采用右美托咪定麻醉,比较两组心率、呼吸频率、血氧饱和度、入睡时间、术后躁动率、不良反应总发生率。结果两组心率、呼吸频率及血氧饱和度比较,差异无统计学意义(P>0.05);研究组入睡时间短于对照组(P<0.05);研究组术后躁动率、不良反应总发生率低于对照组(P<0.05)。结论相较于咪达唑仑,右美托咪定用于小儿手术麻醉能够降低术后躁动率、不良反应发生率,值得推广。Objective To compare the application effect between Dexmedetomidine and Midazolam in pediatric surgical anesthesia.Methods A total of 90 children who underwent surgical anesthesia in Department of Anesthesiology,the Third People’s Hospital of Chengyang District,Qingdao from February 2020 to August 2023 were selected and divided into control group(45 cases)and study group(45 cases)according to the random number table method.The control group was anesthetized by Midazolam,and the study group was anesthetized by Dexmedetomidine.The heart rate,respiration rate,oxyhemoglobin saturation,time of falling asleep,postoperative agitation rate and total incidence of adverse reactions were compared between the two gr oups.Results There were no s ignificant differences in heart rate,respiratory rate and oxyhemoglobin saturation between the two groups(P>0.05).The time of falling asleep in the study group was shorter than that in the control group(P<0.05).The postoperative agitation rate and the total incidence of adverse reactions in the study group were lower than those in the control group(P<0.05).Conclusion Compared with Midazolam,Dexmedetomidine can reduce the rate of postoperative agitation and the incidence of adverse reactions in pediatric surgical anesthesia,which is worth popu larizing.

关 键 词：右美托咪定 咪达唑仑 小儿手术麻醉 术后躁动 不良反应 

分 类 号：R614[医药卫生—麻醉学]