中药保护血管内皮细胞抗动脉粥样硬化作用及其机制研究进展  

Research Progress on the Protective Effect of Traditional Chinese Medicine on Vascular Endothelial Cell Against Atherosclerosis and its Mechanism

作　　者：陈孟佳 吕东岭[2] CHEN Mengjia;LV Dongling(Nanjing University of Chinese Medicine,Nanjing 210000,China;Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210000,China)

机构地区：[1]南京中医药大学,江苏南京210000 [2]南京中医药大学附属医院,江苏南京210000

出　　处：《中国民族民间医药》2024年第1期84-89,共6页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：血管内皮功能障碍是动脉粥样硬化发生和进展中的关键因素,其引起的心脑血管相关疾病,目前在我国死亡原因中居于首位。通过回顾相关文献,分析中药单体及其复方制剂防治动脉粥样硬化的作用和机制,得出中药在保护血管内皮细胞抗动脉粥样硬化方面存在多角度、多层次、多靶点等作用优势,但具体成分之间的相互作用及其机制等仍需更进一步的研讨,进一步明确中药保护血管内皮细胞抗动脉粥样硬化的作用及其机制也将是未来研究的重要方向。Vascular endothelial dysfunction is a key factor in the occurrence and progression of atherosclerosis,and the cardiovascular and cerebrovascular related diseases caused by it are currently the leading cause of death in our country.By reviewing relevant literature and analyzing the effect and mechanism of TCM monomer and its compound preparation on preventing atherosclerosis,it is concluded that TCM has multi-angle,multi-layer and multi-target action advantages in protecting vascular endothelial cells against atherosclerosis,but the interaction between specific components and their mechanism still need further research.It will also be an important direction of future research to further clarify the role and mechanism of Chinese medicine in protecting vascular endothelial cells against atherosclerosis.

关 键 词：动脉粥样硬化 内皮细胞 中药治疗 综述 

分 类 号：R259[医药卫生—中西医结合]