氢溴酸山莨菪碱注射液致味觉障碍合并口干1例  

A case report of taste disorder combined with hypoptyalism induced by anisodamine hydrobromide injection

作　　者：周凯琴 陈秀芬 Kai-Qin ZHOU;Xiu-Fen CHEN(Department of Pharmacy,The 909th Hospital of Joint Logistic Support Force of PLA/Dongnan Hospital of Xiamen University,Zhangzhou 363000,Fujian Province,China)

机构地区：[1]中国人民解放军联勤保障部队第九〇九医院/厦门大学附属东南医院药剂科,福建漳州363000

出　　处：《药物流行病学杂志》2023年第12期1432-1435,共4页Chinese Journal of Pharmacoepidemiology

摘　　要：1例30岁女性患者,因特发性突发性耳聋静脉注射氢溴酸山莨菪碱注射液,连续2 d静注该药10 min后均出现口干、味觉障碍。患者第2次用药后口含冰水,味觉恢复耗时较首次明显缩短。考虑为氢溴酸山莨菪碱注射液的不良反应,停用该药后患者未再出现任何不适。味觉障碍虽不危急生命,但直接影响患者的用药体验与生活质量,临床应提高对此不良反应的认知度和重视度。A 30-year-old female patient with idiopathic sudden hearing loss was treated with anisodamine hydrobromide injection.After 10 minutes of the intravenous injection of this drug,the patient suffered from hypoptyalism and taste disorder for two days.After the second medication,the patient's taste recovery time was significantly shortened by holding the ice water in mouth compared to the first time.Hypoptyalism and taste disorder were considered to be the adverse drug reaction caused by anisodamine hydrobromide injection.After withdrawal the suspected drug,the patient did not experience any further discomfort since.Although taste disorder is not life-threatening,it directly affect the patient's medication experience and quality of life,clinical awareness and attention of the adverse reactions should be increased.

关 键 词：氢溴酸山莨菪碱注射液 味觉障碍 口干 药品不良反应 

分 类 号：R969[医药卫生—药理学]