蜜炙对黄芪成分、药效及应用的影响研究进展  

Research progress in the influence of honey-processing on the chemical composition,pharmacological action and application of Astragali Radix

作　　者：赵婷婷 裴科 于子涵 李鸿昌 孙琳 曹岗[2] 张朔生 胡美变 刘玉杰 蔡皓[3] ZHAO Tingting;PEI Ke;YU Zihan;LI Hongchang;SUN Lin;CAO Gang;ZHANG Shuosheng;HU Meibian;LIU Yujie;CAI Hao(Key Laboratory for Chinese Medicine Processing,School of Chinese Medicine and Food Engineering,Shanxi University of Chinese Medicine,Shanxi Jinzhong 030619,China;Chinese Medicine Processing Research Center,School of Pharmacy,Zhejiang University of Chinese Medicine,Zhejiang Hangzhou 310053,China;Engineering Research Center for the Standardization and Standardization of Chinese Medicine Processing,Ministry of Education,School of Pharmacy,Nanjing University of Chinese Medicine,Jiangsu Nanjing 210023,China)

机构地区：[1]山西中医药大学中药与食品工程学院,山西省中药炮制重点实验室,山西晋中030619 [2]浙江中医药大学药学院,中药炮制研究中心,浙江杭州310053 [3]南京中医药大学药学院,国家教育部中药炮制规范化及标准化工程研究中心,江苏南京210023

出　　处：《中国医院药学杂志》2024年第1期113-122,共10页Chinese Journal of Hospital Pharmacy

基　　金：国家自然科学基金面上项目(编号:82074022);国家自然科学基金联合基金重点项目(编号:U21A20410);山西省中医药管理局科研项目(编号:2022ZYYC265,2023ZYYA033)。

摘　　要：蜜炙黄芪是黄芪经炼蜜闷润炒制而成,是唯一被纳入《中国药典》(2020年版)的黄芪炮制品,被广泛应用于临床。近年来对黄芪和蜜炙黄芪的研究较多,包括小分子成分的鉴定、蜜炙工艺的优化、蜜炙前后成分的变化及药效对比等方面。该文总结了黄芪蜜炙的历史沿革,蜜炙工艺的优化和蜜炙对黄芪成分、药效及临床应用的影响,并指出黄芪蜜炙研究的不足,旨在为蜜炙黄芪的后续研究方向提供依据,为临床两味药的选择应用提供参考。Honey-processed Astragali Radix(HAR)is a commonly used clinical decoction piece which could be obtained by stir-frying the honey soaked Astragali Radix(AR).HAR is the only processed AR included in the Chinese Pharmacopoeia(2020 edition).In recent years,the research on AR and HAR mainly included the identification of small molecular components,optimi⁃zation of honey processing and comparison of pharmacological effects.This article summarized the historical evolution of honey processing,the process optimization,the influence of honey processing on the components,efficacy and clinical application of Astragalus membranaceus,and pointed out the shortcomings of research on the honey processing of AR,so as to provide basis for the subsequent research direction,and provide reference for the selection and application of the two drugs in clinical practice.

关 键 词：黄芪 蜜炙黄芪 历史沿革 工艺 化学成分 药理 临床应用 

分 类 号：R283[医药卫生—中药学]