不同胞元结构多孔钛合金支架的力学性能  

Mechanical Performance of Porous Titanium Alloy Scaffolds with Different Cell Structures

作　　者：孙梦超 罗洋 刘婕[1] 高丽兰[1,3] 李瑞欣 谭沿松 张春秋 SUN Mengchao;LUO Yang;LIU Jie;GAO Lilan;LI Ruixin;TAN Yansong;ZHANG Chunqiu(Tianjin Key Laboratory of Advanced Mechanical and Electrical System Design and Intelligent Control,National Demonstration Center for Experimental Teaching of Mechanical and Electrical Engineering,Tianjin University of Technology,Tianjin 300384,China;Tianjin Medical Devices Supervision and Testing Center,Tianjin 300384,China;Key Laboratory of Bone Implant Interface Functionalization and Personalization Research Enterprise,Just Huajian Medical Device(Tianjin)Co.,Ltd.,Tianjin 300190,China;Tianjin Stomatological Hospital,Tianjin 300041,China)

机构地区：[1]天津理工大学天津市先进机电系统设计与智能控制重点实验室,机电工程国家级实验教学示范中心,天津300384 [2]天津市医疗器械质量监督检验中心,天津300384 [3]嘉思特医疗器材(天津)股份有限公司天津市骨植入物界面功能化与个性研究企业重点实验室,天津300190 [4]天津市口腔医院,天津300041

出　　处：《医用生物力学》2024年第1期69-75,共7页Journal of Medical Biomechanics

基　　金：国家自然科学基金项目(32271371,U23A6009);天津市自然科学多元投入基金面上项目(21JCYBJC00940)。

摘　　要：目的研究不同胞元结构对多孔钛合金支架静态力学性能和动态力学性能的影响,为临床下颌骨缺损修复支架的应用提供力学理论基础。方法采用3D打印技术制造钻石胞元、立方体胞元和截面立方体胞元结构的多孔钛合金支架,开展支架单轴压缩试验和压缩棘轮疲劳试验,分析不同胞元结构支架的静态和动态力学性能。结果钻石胞元、截面立方体胞元、立方体胞元支架的弹性模量分别为1.17、0.566、0.322 GPa,屈服强度分别为71.8、65.1、31.8 MPa。棘轮应变达到稳定阶段后,截面立方体胞元结构、钻石胞元结构、立方体胞元结构支架的棘轮应变分别为3.3%、4.0%、4.5%。棘轮应变随平均应力、应力幅值和峰值保持时间的增加而增加,随加载速率的增加而减小。结论静态力学性能的评估结果为钻石胞元支架最优,截面立方体胞元支架次之,立方体胞元支架最差;动态力学性能评估结果为截面立方体胞元支架最优,钻石胞元支架次之,立方体胞元支架最差。研究结果为临床下颌骨缺损修复支架的构建提供新思路,也为该支架技术的进一步临床应用提供实验依据。Objective To investigate the influence of different cell structures on the static and dynamic mechanical performance of porous titanium alloy scaffolds,and to provide a theoretical mechanical basis for the application of scaffolds in the repair of mandibular bone defects.Methods Porous titanium alloy scaffolds with diamond,cubic,and cross-sectional cubic cell structures were manufactured using three-dimensional printing technology.Uniaxial compression tests and ratcheting fatigue with compression load tests were conducted to analyze the static and dynamic mechanical performances of scaffolds with different cell structures.Results The elastic moduli of the diamond cell,cross-sectional cubic cell,and cubic cell scaffolds were 1.17,0.566,and 0.322 GPa,respectively,and the yield strengths were 71.8,65.1,and 31.8 MPa,respectively.After reaching the stable stage,the ratcheting strains of the cross-sectional cubic,diamond,and cubic cell scaffolds were 3.3%,4.0%,and 4.5%,respectively.The ratcheting strain increased with increasing average stress,stress amplitude,and peak holding time,and decreased with increasing loading rate.Conclusions The evaluation results of the static mechanical performance showed that the diamond cell scaffold was the best,followed by the cross-sectional cubic cell scaffold and the cubic cell scaffold.The evaluation results of the dynamic mechanical performance showed that the cross-sectional cubic cell scaffold performed the best,followed by the diamond cell scaffold,whereas the cubic cell scaffold performed the worst.The fatigue performance of the scaffold is affected by the loading conditions.These results provide new insights for scaffold construction for the repair of mandibular bone defects and provide an experimental basis for further clinical applications of this scaffold technology.

关 键 词：多孔钛合金支架 胞元结构 静态力学性能 动态力学性能 3D打印 

分 类 号：R318.01[医药卫生—生物医学工程]