水凝胶的生物力学研究进展  

Recent Progress in Biomechanical Studies of Hydrogels

作　　者：梁婷 袁章琴 徐静溪 刘禹[1] 李斌[1] LIANG Ting;YUAN Zhangqin;XU Jingxi;LIU Yu;LI Bin(Orthopedic Institute,Soochow University,Suzhou 215000,Jiangsu,China)

机构地区：[1]苏州大学骨科研究所,江苏苏州215000

出　　处：《医用生物力学》2023年第6期1067-1078,共12页Journal of Medical Biomechanics

基　　金：国家自然科学基金项目(32130059,32201070,32171350)。

摘　　要：水凝胶是生物医用领域的重要生物材料,也是近年来的研究热点。但人体内的细胞与组织的微环境和调控机制非常复杂,水凝胶应用于再生修复领域仍存在一些待解决的科学问题。随着生物力学的发展,越来越多的研究者发现除了水凝胶的材料学及生物学特性以外,其生物力学特性也是调控细胞功能、影响组织再生修复的关键因素之一。本文总结了水凝胶材料的生物力学研究进展,并对未来的研究工作进行了展望。Hydrogels are important biomaterials in the field of biomedicine.However,the microenvironment and regulation mechanism of cells and tissues in human body are very complex,and there are still some unsolved scientific issues in the application of hydrogels in the field of regeneration and repair.Along with the development of biomechanics,more and more researchers have found that the biomechanical properties of hydrogels are also one of the key factors in regulating cell function and affecting tissue regeneration and repair,in addition to its material and biological properties.In this review,the biomechanical research progress of hydrogel materials was summarized,and the future research was also prospected.

关 键 词：水凝胶 弹性模量 黏弹性 调控机制 生物力学 

分 类 号：R318.01[医药卫生—生物医学工程]