利用一维Fung模型探讨长宽比对兔腹部皮肤单轴拉伸力学特性的影响  

The Effect of Aspect Ratio on Uniaxial Tensile Mechanical Properties of Rabbit Abdominal Skin Using One-Dimensional Fung Model

作　　者：王辉[1,2] 陈婉婷[1] 孙旭君 李林 刘志成[1,2] WANG Hui;CHEN Wanting;SUN Xujun;LI Lin;LIU Zhicheng(School of Biomedical Engineering,Capital Medical University,Beijing 100069,China;Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application,Capital Medical University,Beijing 100069,China;Imaging Center,Beijing Children Hospital,Capital Medical University,Beijing 100045,China)

机构地区：[1]首都医科大学生物医学工程学院,北京100069 [2]首都医科大学临床生物力学应用基础研究北京市重点实验室,北京100069 [3]首都医科大学附属北京儿童医院影像中心,北京100045

出　　处：《医用生物力学》2023年第6期1235-1240,共6页Journal of Medical Biomechanics

摘　　要：目的 从实验方法学角度研究不同的长宽比对皮肤条状试样单轴拉伸力学特性的影响。方法 以新西兰大白兔腹部皮肤为研究对象,取其从头到脚(0°)和与之垂直(90°)的两个方向,获取长宽比从2∶1~6∶1的多个条状试样,进行单轴拉伸测试至试样破坏。经过实验数据处理,得到兔腹部皮肤单轴拉伸的Kirchhoff应力-Green应变数据,利用一维Fung模型S=cEexp(αE~2)对其进行拟合,从而得到相应的材料参数c、α,并对参数进行统计学分析。结果 两个方向上c值差异不明显(P=0.151),α值差异比较大(P=0.001)。两个方向上不同长宽比兔腹部试样参数c、α无显著性差异(P>0.05)。结论 在2∶1~6∶1长宽比范围内,兔腹部皮肤试样不同长宽比对单轴拉伸力学特性无影响。Objective To investigate the effect of different aspect ratios on uniaxial tensile mechanical properties of skin strip specimens from the perspective of experimental methodology.Methods The abdominal skin of New Zealand rabbits was taken as the research object.Strip specimens with aspect ratios ranging from 2∶1 to 6∶1 were obtained in the direction from the head to the foot(0°) and in the direction perpendicular to it(90°),and uniaxial tensile tests were performed until the specimens were damaged.After experimental data processing,Kirchhoff stress-Green strain data from uniaxial stretch on the abdominal skin of rabbits were obtained and fitted using a one-dimensional Fung model S=cEexp(αE~2),so as to obtain the corresponding material parameters c and α,and statistical analysis of the parameters was performed.Results The differences in c values in two directions were not significant(P=0.151),and the differences in α values were relatively large(P=0.001).There was no significant difference in parameters c and α between rabbit abdominal specimens with different aspect ratios in both directions(P>0.05).Conclusions Different aspect ratios of rabbit abdominal skin specimens in the range from 2∶1 to 6∶1 had no effects on their uniaxial tensile mechanical properties.

关 键 词：长宽比 单轴拉伸 软组织 皮肤 力学特性 

分 类 号：R318.01[医药卫生—生物医学工程]