血液超滤在急性失代偿性心力衰竭中的应用进展  

Progress in the application of blood ultrafiltration in acute decompensated heart failure

作　　者：李昂 杨俊伟[1] LI Ang;YANG Jun-wei(Department of Nephrology,The Second Affiliated Hospital of Nanjing Medical Univers)

机构地区：[1]南京医科大学第二附属医院肾内科,江苏省南京市210000

出　　处：《中国心血管病研究》2024年第2期97-101,共5页Chinese Journal of Cardiovascular Research

基　　金：国家自然科学基金重点项目(81530022)。

摘　　要：心力衰竭(heart failure,HF)是一种全球性的公共卫生问题,急性失代偿性心力衰竭(acute decompensated heart failure,ADHF)作为HF的急性加重阶段,是心源性死亡的主要原因之一,因现有治疗方法的限制,需要探索新的治疗策略。血液超滤作为一种可能的治疗方式,它的理论基础和机制在ADHF治疗中的应用具有特殊的潜力。尽管现有的研究提供了初步的证据支持血液超滤的有效性和安全性,但在ADHF治疗中的应用还面临一些挑战,包括技术限制和治疗效果的不一致,还需要进一步的大规模临床试验和深入的机制研究来验证这些结果。本文旨在综述血液超滤在ADHF中的研究进展。Heart failure(HF)is a global public health problem,among which acute decompensated heart failure(ADHF),as the acute exacerbation stage of HF,is one of the main causes of cardiogenic death.Due to the limitations of the existing treatment methods and relevant unsatisfied result,new treatment strategies need to be explored.Blood ultrafiltration,as a possible treatment method,has special potential in the application on its theoretical basis and mechanism in the treatment of ADHF.Although the existing research provide preliminary evidence to support the effectiveness and safety of blood ultrafiltration,its application in the treatment of ADHF still faces some challenges,including technical limitations and inconsistent treatment outcomes.Further large-scale clinical trials and in-depth mechanistic studies are needed to validate these results.This article aims to review the research progress of blood ultrafiltration in the treatment of ADHF.

关 键 词：心力衰竭 急性失代偿性心力衰竭 血液超滤 液体超负荷 血流动力学 

分 类 号：R541.6[医药卫生—心血管疾病]