一种[60]富勒烯环丙烷二羧酸酯衍生物的合成研究  

The synthesis of novel methano[60]fullerene dicarboxylic acid ester derivatives

作　　者：宋建兴 刘修善 尹少杰 柴明顶 王兴宇 李法宝 SONG Jianxing;LIU Xiushan;YIN Shaojie;CHAI Mingding;WANG Xingyu;LI Fabao(College of Chemistry and Chemical Engineering,Hubei University,Wuhan 430062,China)

机构地区：[1]湖北大学化学化工学院,湖北武汉430062

出　　处：《湖北大学学报（自然科学版）》2024年第2期247-252,共6页Journal of Hubei University：Natural Science

基　　金：国家自然科学基金(22271083);省部共建生物催化与酶工程国家重点实验室(湖北大学)开放基金(SKLBEE2021026);湖北大学大学生创新创业训练计划(X202210512001)资助。

摘　　要：在众多的富勒烯衍生物中,富勒烯环丙烷化合物因其在太阳能电池和生物医药等领域的独特性能而备受关注。但已报道的制备富勒烯环丙烷化合物的方法仍然有一些局限性,例如反应条件苛刻、化学选择性不易控制、反应底物种类有限等。本研究通过[60]富勒烯与碘叶立德的简单一步反应,合成了一系列单加成与多加成富勒烯环丙烷二羧酸酯衍生物。该反应具有操作简单、反应条件温和、产物单一等优点。同时,制备的富勒烯环丙烷二羧酸叔丁酯可以在对甲苯磺酸存在下进行水解,定量转化为水溶性富勒烯环丙烷二羧酸衍生物,增强了富勒烯衍生物在各个领域的潜在应用价值。Among numerous fullerene derivatives,methanofullerenes have attracted special attention due to their unique performance in many fields such as solar cells and biomedicine.However,the reported methods for methanofullerenes still have some synthetic limitations,such as harsh reaction conditions,difficult control of chemoselectivity,and limited types of reaction substrates.In this study,a simple one-step reaction of[60]fullerene with iodonium ylides was studied and a series of monoadditon and multiaddition methanofullerene dicarboxylic acid esters were synthesized.This reaction has the advantages of simple operation,mild reaction conditions,and single product.Meanwhile,the prepared tert-butyl methanofullerene dicarboxylate can be quantitatively hydrolyzed in the presence of p-toluenesulfonic acid to produce water-soluble methanofullerene dicarboxylic acid derivatives,enhancing the potential application value of fullerene derivatives in various fields.

关 键 词：富勒烯 碘叶立德 富勒烯环丙烷二羧酸酯 富勒烯环丙烷二羧酸 

分 类 号：TQ127.1[化学工程—无机化工]