高度近视黄斑出血的中西医研究进展  

Research Progress on Macular Hemorrhage of High Myopiain in Traditional Chinese Medicine and Western Medicine

作　　者：龚新月 毕宏生[2,3] 宋继科 GONG Xingyue;BI Hongsheng;SONG Jike(Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东中医药大学,济南250014 [2]山东中医药大学附属眼科医院,济南250002 [3]山东省眼病防治研究院,济南250002

出　　处：《中国中医眼科杂志》2024年第2期177-180,185,共5页China Journal of Chinese Ophthalmology

基　　金：山东省重点研发计划(重大科技创新工程)项目(2021LCZX09);山东省自然科学基金项目(ZR2021LZY045)。

摘　　要：高度近视并发的眼底病变会造成不可逆的视觉损害,致盲率高。其中高度近视黄斑出血,因其发病位置的特殊性,对患者视力影响极大,且临床上较为常见。本文通过对国内、外文献的整理,针对高度近视黄斑出血的病因病机、影像学表现及中西医治疗进行综述,发现其中医病因主要与肝、脾、肾三脏有关,西医认为发病机制在于黄斑区域脉络膜新生血管形成及眼轴长度延长。主要治疗方法包括西药治疗、手术治疗以及中医方剂、中成药等。但目前缺乏大样本、多中心的临床研究,以及针对不同病因病机的个体化治疗方案。本研究可为高度近视黄斑出血的防治提供一定参考。High myopia-related fundus lesions can result in irreversible visual impairment,with a high risk of blindness.Among these,macular hemorrhage in high myopia significantly impacts patients'vision due to its unique location and is commonly encountered in clinical practice.This paper provides a comprehensive review of the etiology,pathogenesis,imaging manifestations,and treatments in both Traditional Chinese Medicine(TCM)and Western Medicine(WM)for macular hemorrhage in high myopia by compiling and analyzing domestic and foreign literature.It is observed that,the etiology is primarily related to liver,spleen,and kidney in TCM,while WM attributes the pathogenesis to the formation of choroidal neovascularization in the macular region and elongation of the axial length of the eye.Main treatment methods include WM therapy,surgical interventions,as well as TCM prescriptions and patent medicines.However,there is currently a lack of large-sample,multicenter clinical studies and personalized treatment plans tailored to different etiologies and pathogenic mechanisms.This study provides valuable insights for the prevention and treatment of macular hemorrhage in highly myopic individuals.

关 键 词：高度近视 黄斑出血 病因病机 研究进展 

分 类 号：R276.7[医药卫生—中医五官科学]