口服甘露醇助显剂超声在大肠疾病中的应用价值  

Application Value of Oral Mannitol Adjuvant Ultrasound in Colorectal Diseases

作　　者：张美兰 陈海兰 吴圣楠 黄小花[1] 陈燕[1] 徐瑜 刘新秀[1] Zhang Meilan;Chen Hailan;Wu Shengnan;Huang Xiaohua;Chen Yan;Xu Yu;Liu Xinxiu(Department of Ultrasound,The First Affiliated Hospital of Fujian Medical University,Fuzhou 350005,China)

机构地区：[1]福建医科大学附属第一医院超声医学科,福州市350005

出　　处：《中国超声医学杂志》2024年第1期83-86,共4页Chinese Journal of Ultrasound in Medicine

基　　金：福建省科技厅引导性项目(No.2020Y0030)。

摘　　要：目的 探讨口服2.5%甘露醇助显剂超声在大肠疾病中的应用价值。方法 前瞻性收集同时行口服助显剂超声、肠镜及病理检查的所有患者资料,将超声结果与肠镜及病理结果对照,比较两者对大肠病变的检出率及病理符合率,以及口服助显剂超声对大肠常见疾病的诊断效能。结果 共纳入230例患者,口服甘露醇助显剂超声和肠镜分别检出大肠病变203例、229例,与病理相符192例、219例,检出率分别为88.3%、99.6%,诊断符合率分别为83.5%、95.2%。两种方法检出率比较,χ^(2)=25.708,P<0.001,比较两者的病理符合率,χ^(2)=16.651,P<0.001,差异均有统计学意义。口服甘露醇助显剂超声诊断大肠息肉、大肠癌、克罗恩病、溃疡性结肠炎的灵敏度分别为85.4%、88.2%、84.2%、78.6%,特异度分别为99.5%、100%、98.4%、99.1%,阳性预测值分别为97.2%、100%、92.1%、84.6%,阴性预测值分别为96.9%、99.1%、96.9%、98.6%。结论 口服甘露醇助显剂超声是一种有效、经济的无创检查方法,值得临床推广。Objective To evaluate the application value of oral 2.5%mannitol adjuvant ultrasound in colorectal diseases.Methods The data of all patients in our hospital suspected gastrointestinal diseases who underwent oral mannitol adjuvant ultrasound,colonoscopy,and pathological examination were prospectively collected.The results of ultrasound images were compared with those of colonoscopy and pathology,and the diagnostic efficiency of ultrasound was compared with those of colonoscopy and pathology.Results A total of 230 patients were included.Oral mannitol adjuvant ultrasound and colonoscopy detected 203 and 229 cases of colorectal lesions,192 and 219 cases were consistent with pathology,the detection rates of 88.3%and 99.6%,respectively,and the diagnostic coincidence rates were 83.5%and 95.2%,respectively.There was statistically significant difference in the detection rate and pathological coincidence rate between the two methods(P<0.001).The sensitivity of oral mannitol adjuvant ultrasound in diagnosing colorectal polyps,colorectal cancer,Crohn's disease(CD),and ulcerative colitis(UC)was 85.4%,88.2%,84.2%,and 78.6%,the specificity was 99.5%,100%,98.4%,and 99.1%,the positive predictive values were 97.2%,100%,92.1%,and 84.6%,and The negative predictive values were 96.9%,99.1%,96.9%,and 98.6%,respectively.Conclusions Oral mannitol adjuvant ultrasound is an effective,economical and non-invasive examination method,which is worthy of clinical application.

关 键 词：助显剂 超声 甘露醇 大肠疾病 肠镜 

分 类 号：R445.1[医药卫生—影像医学与核医学] R574.6[医药卫生—诊断学]