急性肾衰竭血液灌流联合血液透析治疗期间并发低血压的因素分析  

Analysis of the factors of hypotension during hemoperfusion combined with hemodialysis for patients with acute renal failure

作　　者：王静霞[1] 陈智红[1] 习晓红 张唤 李春珍[1] 叶风芳 董洁景[1] WANG Jingxia;CHEN Zhihong;XI Xiaohong;ZHANG Huan;LI Chunzhen;YE Fengfang;DONG Jiejing(Department of Renal Immunology,Hebei Children's Hospital,Shijiazhuang Hebei 050030,China)

机构地区：[1]河北省儿童医院肾脏免疫科,河北石家庄050030

出　　处：《中国急救复苏与灾害医学杂志》2024年第1期90-92,140,共4页China Journal of Emergency Resuscitation and Disaster Medicine

基　　金：2018年度河北省医学科学研究重点课题计划(编号:20180618)。

摘　　要：目的 分析急性肾衰竭(ARF)血液灌流联合血液透析治疗期间并发低血压的因素。方法 回顾性分析2020年1月—2022年12月于河北省儿童医院接受血液灌流联合血液透析治疗的儿童303例ARF患者临床资料,根据患者3个月内治疗期间有无并发低血压分为并发低血压组(n=61)与未并发低血压组(n=242);采用Logistic回归分析筛选影响ARF血液灌流联合血液透析治疗期间并发低血压的危险因素。结果 303例ARF患者共61例并发低血压(占20.13%)。Logistic回归分析结果显示,高通量透析方式(95%CI 1.196~4.984,P=0.014)、血流量>300 mL/min(95%CI 1.056~4.851,P=0.036)、血红蛋白(95%CI 0.444~0.703,P=0.000)、白蛋白(95%CI 0.153~0.833,P=0.017)均是ARF血液灌流联合血液透析治疗期间并发低血压的重要影响因素(P<0.05)。结论 高通量透析方式、血流量>300 mL/min、血红蛋白、白蛋白均是ARF血液灌流联合血液透析治疗期间并发低血压的重要影响因素。Objective To analyze the factors of hypotension during hemoperfusion combined with hemodialysis for patients with acute renal failure(ARF).Methods The clinical data of 303 patients with ARF who received hemoperfusion combined with hemodialysis in hebei Children's Hospital from January 2020 to December 2022 were analyzed retrospectively,the patients were grouped into hypotension group(n=61)and non-hypotension group(n=242)according to whether there was hypotension during the treatment within 3 months;Logistic regression analysis was applied to screen the risk factors of hypotension during hemoperfusion combined with hemodialysis for ARF.Results 61 of 303 ARF patients who received hemoperfusion combined with hemodialysis in our hospital were complicated with hypotension(20.13%).Logistic regression analysis showed that high-throughput dialysis(95%CI 1.196-4.984,P=0.014),blood flow>300 mL/min(95%CI 1.056-4.851,P=0.036),hemoglobin(95%CI 0.444-0.703,P=0.000)and albumin(95%CI 0.153-0.833,P=0.017)were important influencing factors of hypotension during ARF combined with hemodialysis treatment(P<0.05).Conclusion High flux dialysis,blood flow>300 mL/min,hemoglobin and albumin are important influencing factors of hypotension during the treatment of hemoperfusion combined with hemodialysis for ARF.

关 键 词：急性肾衰竭 血液灌流 血液透析 低血压 因素 

分 类 号：R692.5[医药卫生—泌尿科学]