造血干细胞移植患者术后症状群的范围综述  

Postoperative symptom cluster of hematopoietic stem cell transplantation patients:a scoping review

作　　者：胥晨逸 叶梦华 曹敏 徐敏[3] Xu Chenyi;Ye Menghua;Cao Min;Xu Min(School of Nursing,Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Hematology,the First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China;Hospital Management Office,the First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China)

机构地区：[1]浙江中医药大学护理学院,杭州310053 [2]浙江中医药大学第一附属医院血液科,杭州310006 [3]浙江中医药大学第一附属医院管理办公室,杭州310006

出　　处：《中华现代护理杂志》2024年第5期678-683,共6页Chinese Journal of Modern Nursing

基　　金：浙江省医药卫生科技计划项目(2023KY139)。

摘　　要：目的对造血干细胞移植(HSCT)患者症状群研究文献进行范围综述,旨在为完善HSCT患者术后症状群管理提供参考。方法检索PubMed、Web of Science、CINAHL、Embase、Cochrane Library、中国知网、中国生物医学文献库、维普网、万方数据库中收录的HSCT患者术后症状群的相关研究,检索时限为建库至2023年7月17日。结果共纳入10篇文献,提取症状群9种,频次排在前3位的分别为疲乏相关、消化道相关及心理症状群。症状群的影响因素主要包括慢性移植物抗宿主病、移植类型、预处理方案、性别、抑郁水平等。HSCT患者症状群评估工具的异质性较高。结论HSCT患者术后症状群的动态变化受多种因素影响,特异性测评工具仍有待开发。Objective To conduct a scoping review on symptom cluster of hematopoietic stem cell transplantation(HSCT)patients,aiming to provide reference for improving postoperative symptom management in HSCT patients.Methods The study on postoperative symptom clusters in HSCT patients was searched in PubMed,Web of Science,CINAHL,Embase,Cochrane Library,China National Knowledge Infrastructure,Chinese Biomedical Database,VIP,and WanFang Data.The search period was from database establishment to July 17,2023.Results A total of 10 articles were included,and 9 symptom clusters were extracted.The top three symptom clusters in terms of frequency were fatigue related,gastrointestinal related,and psychological symptom clusters.The influencing factors of symptom cluster mainly included chronic graft-versus-host disease,transplant type,conditioning regimen,gender,depression level and so on.The heterogeneity of HSCT patient symptom cluster assessment tools was relatively high.Conclusions The dynamic changes of postoperative symptom clusters in HSCT patients are influenced by multiple factors,and specific assessment tools still need to be developed.

关 键 词：综述 造血干细胞移植 症状群 症状负担 

分 类 号：R457.7[医药卫生—治疗学]