中医药治疗糖尿病胃轻瘫作用机制的研究现状  

Research status on the mechanism of traditional Chinese medicine in the treatment of diabetic gastroparesis

作　　者：陈琼 沈贤敏[1,2] 王斐 许恒[1,2] CHEN Qiong;SHEN Xian-min;WANG Fei;XU Heng(Central Laboratory,Suzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou 215009,Jiangsu Province,China;Clinical Pharmaceutical Laboratory of Traditional Chinese Medicine,Suzhou Academy of Wumen Chinese Medicine,Suzhou 215009,Jiangsu Province,China)

机构地区：[1]南京中医药大学附属苏州市中医医院中心实验室,江苏苏州215009 [2]苏州市吴门医派研究院中药临床药学实验室,江苏苏州215009

出　　处：《中国临床药理学杂志》2024年第3期459-463,共5页The Chinese Journal of Clinical Pharmacology

基　　金：国家自然基金科学基金资助项目(81903899);苏州市姑苏卫生人才计划基金资助项目(GSWS2020089);苏州市科技基金资助项目(SYSD2016134,SKY2023217,SKYD2023155);中医骨伤重点实验室建设基金资助项目(JSDW202253,SZS2022019)。

摘　　要：中医药在糖尿病胃轻瘫(DGP)的临床防治实践中具有一定的特色和优势。本文通过对近年来关于中医药治疗DGP的国内外研究进行整理和综述,发现中医药可以通过调节Cajal间质细胞、肠神经系统、胃肠激素、肠道菌群等方面发挥作用。本文从上述几个方面对中医药治疗DGP的作用机制研究进展进行论述,为DGP的防治提供思路和科学依据。Objective Traditional Chinese medicine(TCM) has precise traits and advantages in the scientific prevention and remedy practice of diabetic gastroparesis(DGP).The review gathered and reviewed the research on the therapy of DGP with TCM in current years.It was once located that it performed an essential function by regulating Cajal interstitial cells,enteric nervous system,gastrointestinal hormones and gut microbiota.The research development of the mechanism and effect of TCM in the treatment of DGP were respectively reviewed from the above factors,providing thoughts and scientific foundation for the prevention and treatment of DGP.

关 键 词：中医药 糖尿病胃轻瘫 机制 CAJAL间质细胞 胃肠激素 

分 类 号：R28[医药卫生—中药学]