Numerical analysis of hemodynamic parameters in stenosed arteries under pulsatile flow conditions  

作　　者：Priyambada Praharaj Chandrakant Sonawane Anand Pandey Vikas Kumar Arundhati Warke Hitesh Panchal R.Ibrahim Chander Prakash 

机构地区：[1]Jayawant Shikshan Prasarak Mandal(JSPM)’s Rajarshi Shahu College of Engineering,Pune,India [2]Symbiosis Institute of Technology,Symbiosis International Deemed University,Pune,India [3]Centre for Development of Advanced Computing(CDAC),Pune,India [4]Department of Mechanical Engineering,Government Engineering College patan,Gujarat,India [5]Department of medical instruments engineering techniques,Al-farahidi University,Baghdad,Iraq [6]Research&Developemnt,SVKM’S Narsee Monjee Institute of Management Studies,Mumbai,India [7]Mukesh Patel School of Technology Management and Engineering,SVKM’S Narsee Monjee Institute of Management Studies,Mumbai,India

出　　处：《Medicine in Novel Technology and Devices》2023年第4期32-50,共19页医学中新技术与新装备（英文）

摘　　要：This research studies the changes in flow patterns and hemodynamic parameters of diverse shapes and sizes of stenosis.Six different shapes and sizes of stenosis are constructed to investigate the variations in hemodynamics as the morphology changes.Changes in shape(trapezoidal and bell-shaped)and sizes of stenosis change the stresses on the walls and their flow patterns.TAWSS and OSI results specify that trapezoidal stenosis exerts greater stress than bell-shaped stenosis.Also,as the length of the trapezoidal stenosis increases,the TAWSS increases,whereas the trend is the opposite for bell-shaped stenosis.Later,this paper also studies different degrees of stenosis extracted from real images.Changes in velocity flow patterns,wall shear stress(WSS),Time-averaged wall shear stress(TAWSS)and Oscillatory shear index(OSI)have been studied for these images.Results illustrate that the peak velocity rises drastically as the stenosis percentage increases.Negative velocity is seen close to the artery's walls,indicating flow separation.This flow separation region is seen throughout the cycle except in the accelerating flow region.An increase in stenosis also increases WSS and TAWSS drastically.Negative WSS is seen downstream of stenosis,indicating flow recirculation.Such negative WSS in the blood vessels also promotes endothelial dysfunction.OSI values greater than 0.2 are seen near the stenosis region,indicating atherosclerosis growth.Regions of high OSI and low TAWSS are also identified,indicating probable regions of plaque development.

关 键 词：CARDIOVASCULAR Stenosis morphology Real geometry CFD simulation Artificial compressibility method HLLC-AC Pulsatile velocity 

分 类 号：R31[医药卫生—基础医学]