多发子宫肌瘤剔除术后患者再次复发风险评估列线图模型的构建  

Construction of a Nomogram model for risk asesment of recurrence in patients after multiple sshysteromyomectomy

作　　者：殷平平 张岩 邵小姣 YIN Pingping;ZHANG Yan;SHAO Xiaojiao(Department of Obstetrics and Gynecology,17th Metallurgical Hospital in Ma′anshan,Ma′anshan 243000,Anhui,China)

机构地区：[1]安徽省马鞍山十七冶医院妇产科,安徽马鞍山243000

出　　处：《中国性科学》2024年第2期93-96,共4页Chinese Journal of Human Sexuality

基　　金：2019年安徽省重点研究与开发计划项目(201904a07020094)。

摘　　要：目的构建多发子宫肌瘤剔除术后患者再次复发风险评估的列线图模型。方法选取2019年7月至2020年2月间安徽省马鞍山十七冶医院收治的102例行多发子宫肌瘤剔除术的患者作为研究对象,按照患者剔除术后是否再次复发分为复发组(n=37)和未复发组(n=65)。记录并比较患者临床资料,采用Spearman相关性检验分析各指标与术后再次复发的相关性;采用Logistic回归模型分析各指标影响术后再次复发的危险因素;构建列线图模型评估多发子宫肌瘤剔除术后再次复发的风险,绘制受试者工作特征(ROC)曲线分析列线图模型的预测价值。结果复发组和未复发组年龄、体重指数、子宫肌瘤长径、肌瘤数目、术后药物治疗存在显著差异(P<0.05)。患者年龄、术后药物治疗、体重指数、子宫肌瘤长径、肌瘤数目与多发子宫肌瘤剔除术后患者再次复发呈显著相关性(P<0.05);低龄、高体重指数、长子宫肌瘤长径、多肌瘤数目及未采用术后药物治疗是影响多发子宫肌瘤剔除术后患者再次复发的独立危险因素(P<0.05)。将年龄、体重指数、子宫肌瘤长径、肌瘤数目、术后药物治疗作为多发子宫肌瘤剔除术后再次复发风险的列线图模型参数可有效构建预测模型,其预测再次复发的曲线下面积(AUC)为0.961(P<0.05)。结论采用年龄、体重指数、子宫肌瘤长径、肌瘤数目、术后药物治疗构建的多发子宫肌瘤剔除术后患者再次复发风险的列线图模型可有效预测术后再次复发的风险。Objective To construct a Nomogram model for risk assessment of recurrence in patients after multiple hysteromyomectomy.Methods A total of 102 patients after multiple hysteromyomectomy who were admitted to 17th Metallurgical Hospital in Ma′anshan between July 2019 and February 2020 were selected as the research objects.They were divided into recurrence group(n=37)and non-recurrence group(n=65)according to the recurrence or not after myomectomy.The clinical data of the patients were recorded and analyzed.Spearman correlation analysis was used to analyze the correlation between each parameter and postoperative recurrence.Logistic regression model was used to analyze the risk factors of postoperative recurrence for each parameter.A Nomogram model was constructed to evaluate risk of recurrence after multiple hysteromyomectomy.Receiver operating characteristic(ROC)curve was drawn to analysis the predictive value of Nomogram models.Results There were significant differences in age,body mass index,long-diameter of uterine fibroids,number of fibroids,and postoperative drugs treatment between the recurrence group and the non-recurrence group(P<0.05).Patients′age,postoperative drug treatment,body mass index,long-diameter of uterine fibroids,and number of fibroids were significantly correlated with recurrence after multiple hysteromyomectomy(P<0.05).Younger age,high body mass index,long long-diameter of uterine fibroids,high number of fibroids,and no postoperative drug treatment were independent risk factors for recurrence in patients after multiple hysteromyomectomy(P<0.05).The prediction model can be effectively constructed when using age,body mass index,long diameter of uterine fibroids,the number of fibroids,and postoperative drug treatment as the parameters of the Nomogram model for recurrence risk after multiple hysteromyomectomy,and the area under ROC curve(AUC)for recurrence prediction is 0.961(P<0.05).Conclusions Risk of postoperative recurrence can be effectively predicted by using age,body mass index,long diam

关 键 词：多发子宫肌瘤剔除术 术后再次复发 列线图模型 

分 类 号：R711[医药卫生—妇产科学]